Université Paris-Saclay, UVSQ, Inserm, Gustave Roussy, CESP, 94805, Villejuif, France.
Inserm, Université Paris Cité, Université Paris Saclay, Université de Versailles-Saint-Quentin-en-Yvelines (UVSQ), UMS 011 « Population-based cohorts unit », Villejuif, France.
J Am Med Dir Assoc. 2024 Feb;25(2):266-274. doi: 10.1016/j.jamda.2023.10.001. Epub 2023 Nov 6.
Walking speed (WS) represents an objective measure of motor function and health. We aimed to develop usual (UWS) and fast WS (FWS) norms for the general population using a regression-based approach, while considering age, sex, height, and education.
Cross-sectional analysis of a population-based study.
French Constances study (45-69 years).
UWS/FWS were measured over 3 m (dynamic start) using photoelectric cells. We addressed selection effects (related to survey sampling and nonresponse) and missing data using a combination of inverse probability weighting (IPW) and multiple imputation (MI). Norms by sex, age, height, and education (<tertiary/≥tertiary) were estimated using a 3-level linear mixed effects model (random effects on center and year) allowing for nonlinear relations that were adjusted for age, sex, height, education, and significant 2-way interactions.
Analyses are based on 44,772 participants (51.2% women) with a mean age of 56.8 years (SE = 0.2) for women and 57.3 years (SE = 0.2) for men, and a mean height of 161.4 cm (SE = 0.1) for women and 174.2 cm (SE = 0.1) for men after IPW/MI. WS estimates decreased after IPW/MI. The mean UWS was 116.9 cm/s (SE = 0.8) in women and 120.7 cm/s (SE = 0.8) in men, and the mean FWS was 168.7 cm/s (SE = 1.0) in women and 182.8 cm/s (SE = 1.2) in men. In the multiadjusted model, UWS/FWS decreased with age and increased with height and education. Men had faster FWS than women; they had slightly slower UWS than women in the low-education group, but there were no sex differences in the high-education group.
We developed UWS/FWS norms by age, sex, height, and education for the French general population (45-69 years) that are available through a web app (https://cesp-proxy2.vjf.inserm.fr/NORMES-VM-EN/). These norms can be used to identify in midlife persons with lower motor performances than the general population, given their age, sex, height, and education, who are at higher risk of adverse outcomes.
步行速度(WS)是衡量运动功能和健康的客观指标。我们旨在使用基于回归的方法为普通人群制定常用(UWS)和快速 WS(FWS)标准,同时考虑年龄、性别、身高和教育程度。
基于人群的横断面分析。
法国康斯坦茨研究(45-69 岁)。
使用光电管在 3 米(动态开始)上测量 UWS/FWS。我们通过逆概率加权(IPW)和多重插补(MI)的组合解决选择效应(与调查抽样和无应答有关)和缺失数据问题。根据性别、年龄、身高和教育程度(<高等教育/≥高等教育)使用 3 级线性混合效应模型(中心和年份的随机效应)估计了 UWS/FWS 标准,该模型允许非线性关系调整为年龄、性别、身高、教育程度和显著的 2 向交互作用。
分析基于 44772 名参与者(51.2%为女性),女性的平均年龄为 56.8 岁(SE=0.2),男性为 57.3 岁(SE=0.2),女性平均身高为 161.4 厘米(SE=0.1),男性为 174.2 厘米(SE=0.1),经 IPW/MI 后。WS 估计值在 IPW/MI 后下降。女性的平均 UWS 为 116.9cm/s(SE=0.8),男性为 120.7cm/s(SE=0.8),女性的平均 FWS 为 168.7cm/s(SE=1.0),男性为 182.8cm/s(SE=1.2)。在多调整模型中,UWS/FWS 随年龄增长而降低,随身高和教育程度增加而增加。男性的 FWS 比女性快;在低教育组中,他们的 UWS 比女性略慢,但在高教育组中没有性别差异。
我们为法国普通人群(45-69 岁)制定了按年龄、性别、身高和教育程度划分的 UWS/FWS 标准,这些标准可通过网络应用程序(https://cesp-proxy2.vjf.inserm.fr/NORMES-VM-EN/)获得。这些标准可用于识别处于中年的人群,他们的运动表现低于普通人群,考虑到他们的年龄、性别、身高和教育程度,他们面临更高的不良后果风险。