Serviço de Ginecologia e Obstetrícia, Hospital Beatriz Ângelo, Loures, Portugal.
Serviço de Dermatologia, Centro Hospitalar Universitário de Lisboa Norte, Lisboa, Portugal.
Rev Bras Ginecol Obstet. 2023 Oct;45(10):e568-e574. doi: 10.1055/s-0043-1772481. Epub 2023 Nov 9.
Pregnancy in women with lupus poses a higher risk of complications compared with the general population. The present study aimed to determine and describe the obstetric and neonatal outcomes of pregnant women with lupus.
We conducted an observational retrospective study of pregnant women with the diagnosis of lupus, who were selected and followed at the Maternal-Fetal Medicine Clinic of our institution between January 2013 and July 2018. We analyzed 59 pregnancies and 52 newborns, and collected data regarding sociodemographic features, the preconception period, pregnancy, childbirth, postpartum and the newborn. A descriptive analysis of the variables was performed.
In 58% of the cases, the pregnancy was uneventful. We registered flares in 25% of the cases, preeclampsia in 3%, fetal growth restriction in 12%, gestational loss in 10%, preterm labor in 10%, postpartum complications in 20%, and small for gestational age newborns in 17% of the cases.
Most pregnancies in women with lupus have favorable obstetric and neonatal outcomes. Prenatal counseling, adequate multidisciplinary surveillance, and optimized treatment of the disease are fundamental pillars for these good results.
与普通人群相比，狼疮女性怀孕存在更高的并发症风险。本研究旨在确定和描述狼疮孕妇的产科和新生儿结局。
我们对 2013 年 1 月至 2018 年 7 月在我们机构的母胎医学诊所被诊断为狼疮的孕妇进行了一项观察性回顾性研究。我们分析了 59 例妊娠和 52 例新生儿，并收集了有关社会人口统计学特征、孕前、妊娠、分娩、产后和新生儿的数据。对变量进行了描述性分析。
在 58%的病例中，妊娠无并发症。我们记录了 25%的病例出现疾病活动，3%的病例出现子痫前期，12%的病例出现胎儿生长受限，10%的病例出现妊娠丢失，10%的病例出现早产，20%的病例出现产后并发症，17%的病例出现小于胎龄儿。
大多数狼疮女性的妊娠有良好的产科和新生儿结局。产前咨询、充分的多学科监测以及疾病的优化治疗是取得这些良好结果的基本支柱。
