Department of Radiology (Campus Charité Mitte), Charité Universitätsmedizin Berlin, Germany.
Charité - Universitätsmedizin, Berlin Institute of Health at Charite, Berlin, Germany.
Rofo. 2024 Jun;196(6):550-559. doi: 10.1055/a-2193-1970. Epub 2023 Nov 9.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease primarily affecting the sacroiliac joints (SIJs) and the spine. Imaging plays a crucial role in the diagnosis of axSpA, with magnetic resonance imaging (MRI) and radiography being the primary modalities used in clinical practice. New bone formation occurs in both the spine (non-bridging and bridging syndesmophytes, transdiscal ankylosis, and ankylosis of small joints and posterior elements) and the SIJs (backfill and ankylosis). New bone formation indicates advanced axSpA.
This review explores the role of imaging in the diagnosis and monitoring of axSpA, focusing on the significance of new bone formation, and provides an overview of the characteristic imaging findings of new bone formation in axSpA in each imaging modality.
Imaging methods, such as X-ray, MRI, and CT, have different diagnostic accuracies for detecting structural lesions and new bone formation. Each modality has its strengths and weaknesses, and the choice depends on the specific clinical context. Imaging is crucial for the diagnosis and monitoring of axSpA, particularly for the detection of new bone formation. Different imaging techniques provide valuable information about disease progression and treatment response. Understanding the significance of new bone formation and its detection using imaging modalities is essential for the accurate diagnosis and effective management of patients with axSpA.
New bone formation is a hallmark feature of advanced axial spondyloarthritis. New bone formation occurs both in the spine and in the sacroiliac joints. Differentiation of new bone formation in axial spondyloarthritis from that in other conditions such as diffuse idiopathic skeletal hyperostosis and from osteophytes is essential. Imaging methods, such as X-ray, MRI, and CT, have different diagnostic accuracies for detecting new bone formation.
Ulas S, Deppe D, Ziegeler K et al. New Bone Formation in Axial Spondyloarthritis: A Review. Fortschr Röntgenstr 2024; 196: 550 – 559.
中轴型脊柱关节炎（axSpA）是一种主要影响骶髂关节（SIJ）和脊柱的慢性炎症性疾病。影像学在 axSpA 的诊断中起着至关重要的作用，磁共振成像（MRI）和 X 线摄影是临床实践中主要使用的方式。在脊柱（非桥接和桥接骨桥、椎间盘强直和小关节及后结构强直）和 SIJ（填充和强直）中均会出现新骨形成。新骨形成表明 axSpA 处于晚期。
本综述探讨了影像学在 axSpA 的诊断和监测中的作用，重点介绍了新骨形成的意义，并概述了每种影像学方式中 axSpA 新骨形成的特征性影像学表现。
X 线、MRI 和 CT 等影像学方法对检测结构病变和新骨形成的诊断准确性不同。每种方式都有其优势和局限性，选择取决于具体的临床情况。影像学对于 axSpA 的诊断和监测至关重要，特别是对新骨形成的检测。不同的影像学技术提供了关于疾病进展和治疗反应的有价值的信息。了解新骨形成及其在影像学中的检测对于 axSpA 患者的准确诊断和有效管理至关重要。
新骨形成是中轴型脊柱关节炎晚期的一个标志性特征。新骨形成既发生在脊柱，也发生在骶髂关节。区分 axSpA 中的新骨形成与弥漫性特发性骨肥厚和骨赘中的新骨形成至关重要。X 线、MRI 和 CT 等影像学方法对检测新骨形成的诊断准确性不同。
Ulas S, Deppe D, Ziegeler K 等。轴向脊柱关节炎中的新骨形成：综述。Fortschr Röntgenstr 2024; 196: 550-559.
