Efficacy of Getong Tongluo Capsule plus Clopidogrel hydrogen sulfate tablets Therapy Assisted by Home Rehabilitation Guidance in Convalescents from Cerebral Infarction.

BACKGROUND

Cerebral infarction (CI) is one of the leading causes of death in middle-aged and elderly people, and there is a need to focus on overall rehabilitation during the recovery period of CI in the clinic, to provide a more reliable guarantee for the health of patients.

OBJECTIVE

To observe the therapeutic efficacy of Getong Tongluo Capsule (GTC) plus Clopidogrel hydrogen sulfate tablets (CHST) therapy assisted by home rehabilitation guidance in convalescents from CI, to provide clinical reference and evidence for future CI management.

METHODS

CI convalescents who visited the Fourth People's Hospital of Haikou City between 2016 and 2021 were selected as the research participants. Based on the assistance of home rehabilitation guidance, 44 patients receiving CHST treatment and 56 patients receiving GTC + CHST treatment were assigned to a control group (CG) and research group (RG), respectively. The blood viscosity of the two groups was compared before and after treatment. In addition, patients were assessed by the National Institutes of Health Stroke Scale (NIHSS), Mini-Mental State Examination (MMSE), Fugl-Meyer Assessment (FMA), Modified Barthel index (MBI), and Self-rating Anxiety/Depression Scale (SAS/SDS) scores. Finally, the adverse reaction rate was counted.

RESULTS

The post-treatment blood viscosity decreased in both cohorts and was lower in RG compared with CG (P < .001). Regarding various scale scores, NIHSS, SAS, and SDS were lower in RG than CG, while MMSE, FMA, and MBI were higher (P < .001). The adverse reaction rate was not significantly different between groups (P = .587).

CONCLUSION

GTC + CHST therapy assisted by home rehabilitation guidance is effective in the treatment of CI patients in the convalescent stage and is worth recommending.