Virtanen M T
J Environ Pathol Toxicol Oncol. 1986 Sep-Dec;7(1-2):73-85.
After exposure to 1.2-3.0 ppb of DDT in an aquatic-terrestrial model ecosystem, the gills of guppies showed histopathological changes when examined by light and electron microscopy. The secondary lamellae of the gills were shortened and deformed and the epithelial cells were disoriented with regard to the pillar cell system. In many places erythrocytes were virtually absent from the blood laguna, which was filled with the flanges of pillar cells. The microfilament bundles in the pillar cell cytoplasm had disintegrated. The chloride cells were swollen and alterations had occurred in their mitochondria and nuclei. The changes did not resemble the typical non-specific pattern of pesticide poisoning, and were probably specific to DDT.
在一个水陆生态模型系统中，孔雀鱼暴露于1.2 - 3.0 ppb的滴滴涕后，用光镜和电镜检查时，其鳃显示出组织病理学变化。鳃的次生鳃小片缩短且变形，上皮细胞相对于柱状细胞系统排列紊乱。在许多地方，血液淋巴窦中几乎没有红细胞，取而代之的是充满了柱状细胞的翼状突起。柱状细胞细胞质中的微丝束已经解体。氯细胞肿胀，其线粒体和细胞核也发生了变化。这些变化与典型的农药中毒非特异性模式不同，可能是滴滴涕所特有的。
