Zola-Morgan S, Micheletti C
J Med Primatol. 1986;15(6):399-408.
Respiration rate, heart rate, and body temperature values were obtained from 14 cynomolgus monkeys (Macaca fascicularis) during neurosurgery under barbiturate anesthesia. Vital sign values markedly declined below baseline during the early stages of surgery, steadily increased as surgery progressed and neared completion, and finally returned to baseline by the end of the postsurgical recovery period. There was considerable variability among the 14 monkeys, but the ranking of each monkey relative to the others remained constant across the period of observation. The findings suggested that the cynomolgus monkey may be more sensitive to barbiturates than the rhesus monkey, and cynomolgus monkeys may exhibit considerable individual differences in their sensitivity to barbiturates.
在巴比妥类麻醉下进行神经外科手术期间，从14只食蟹猴（猕猴）获取了呼吸频率、心率和体温值。生命体征值在手术早期显著低于基线水平，随着手术进展并接近完成时稳步上升，最终在术后恢复期结束时恢复到基线水平。14只猴子之间存在相当大的变异性，但在观察期间，每只猴子相对于其他猴子的排名保持不变。这些发现表明，食蟹猴可能比恒河猴对巴比妥类药物更敏感，并且食蟹猴在对巴比妥类药物的敏感性方面可能表现出相当大的个体差异。
