Pérez-Solá Víctor, Montes José M, Trillo-Calvo Eva, Gasull Vicente, García-Campayo Javier, Olivares-Diez Jose Manuel, Berrocoso Esther, Mico Juan Antonio, Agüera-Ortiz Luis
Director of Healthcare and Medical Area, Hospital del Mar, Barcelona, Spain; Biomedical Research Network in Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain; Director of the Institute of Mental Health, Hospital del Mar, Barcelona, Spain; Pompeu Fabra University, Barcelona, Spain.
Biomedical Research Network in Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain; Ramón y Cajal University Hospital, IRYCIS, Madrid, Spain; University of Alcalá, Alcala de Henares, Spain.
Span J Psychiatry Ment Health. 2025 Jan-Mar;18(1):21-27. doi: 10.1016/j.sjpmh.2023.10.002. Epub 2023 Nov 10.
Globally, depression is the most common psychiatric disorder and is frequently associated with somatic symptom disorders, including pain as a physical symptom. There is a current need to improve the detection and management of the individuals in which depression and pain coexist. Hence, the aim of this document is to provide recommendations in the diagnosis and management of patients with major depressive disorder (MDD) who have pain as a physical symptom (PPS), in order to reduce the variability of clinical practice.
The methodology used is based on the internationally recognized RAND/UCLA consensus method. The scientific committee, consisted of a group of eight multidisciplinary experts, defined 12 clinically relevant questions. After the systematic review of the literature, the scientific committee assessed the evidence and developed recommendations. The panel group with 15 participants validated these recommendations using a single Delphi round. To conclude, there was a final consensus meeting held to redefine with minor modifications the final recommendations.
The scientific committee developed a total of 19 recommendations on the diagnosis and detection, impact of PPS in MDD, treatment of MDD with associated PPS, use of healthcare resources, additional recommendations, and care coordination of these patients. Globally, a substantial level of agreement (≥80%) was reached on all items during the Delphi round. All the 19 achieved consensus, seven of them (37%) were agreed with unanimity during the Delphi round. The recommendations with higher consensus were in relation to diagnosis, impact of PPS in MDD, treatment and use of healthcare resources.
Currently, the evidence base for patients with MDD and PPS is still being developed and this consensus statement aims to bridge that gap by providing practical recommendations.
在全球范围内,抑郁症是最常见的精神障碍,常与躯体症状障碍相关,包括疼痛这一躯体症状。当前需要改善对抑郁症和疼痛共存个体的检测与管理。因此,本文档的目的是为伴有疼痛躯体症状(PPS)的重度抑郁症(MDD)患者的诊断和管理提供建议,以减少临床实践的差异。
所采用的方法基于国际认可的兰德/加州大学洛杉矶分校共识方法。科学委员会由八名多学科专家组成,确定了12个临床相关问题。在对文献进行系统综述后,科学委员会评估证据并制定建议。由15名参与者组成的专家组通过一轮德尔菲法验证了这些建议。最后,召开了一次最终共识会议,对最终建议进行了微调后重新确定。
科学委员会就这些患者的诊断与检测、PPS对MDD的影响、伴有PPS的MDD的治疗、医疗资源的使用、其他建议以及护理协调共制定了19条建议。总体而言,在德尔菲法过程中,所有项目均达成了较高程度的一致(≥80%)。所有19条建议均达成了共识,其中7条(37%)在德尔菲法过程中获得了一致同意。共识度较高的建议涉及诊断、PPS对MDD的影响、治疗以及医疗资源的使用。
目前针对MDD和PPS患者的证据基础仍在发展中,这份共识声明旨在通过提供实用建议来弥合这一差距。