Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Department of Radiology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Intern Med. 2024 Jun 15;63(12):1675-1681. doi: 10.2169/internalmedicine.2771-23. Epub 2023 Nov 13.
Objective Myocardial crypts are congenital abnormalities associated with hypertrophic cardiomyopathy (HCM) and other conditions. This study assessed the prevalence of myocardial crypts in Japanese patients. Methods Myocardial crypts were evaluated in a consecutive series of 300 patients (13-92 years old) who underwent computed tomography angiography (CTA) because of clinical suspicion of ischemic heart disease. Results We found a myocardial crypt incidence of 9.7% (29 patients) in our study population, with multiple crypts observed in 2.3% (7 patients). Among these, myocardial crypts were found in 2 out of 8 (25%) patients with hypertrophic cardiomyopathy (HCM), 1 of which was apical-type HCM. In patients with a single crypt (22 patients), the most common location of the crypt was at the left ventricular apex (16/22 patients, 72.7%), followed by the inferior wall (5/22 patients, 22.7%) and the interventricular septum (1/22 patients, 4.6%). Conclusion The incidence of myocardial crypts observed in our study aligns with that reported in previous studies, although the most common location among the Japanese population was the left ventricular apex.
心肌隐窝是与肥厚型心肌病（HCM）和其他疾病相关的先天性异常。本研究评估了日本患者中心肌隐窝的患病率。
对因临床疑似缺血性心脏病而接受计算机断层扫描血管造影（CTA）的 300 例连续患者（13-92 岁）进行了心肌隐窝评估。
在我们的研究人群中，发现心肌隐窝的发生率为 9.7%（29 例），其中 2.3%（7 例）存在多发隐窝。其中，2 例肥厚型心肌病（HCM）患者存在心肌隐窝，其中 1 例为心尖肥厚型 HCM。在存在单个隐窝的 22 例患者中，隐窝最常见的部位为左心室心尖（16/22 例，72.7%），其次为下壁（5/22 例，22.7%）和室间隔（1/22 例，4.6%）。
本研究观察到的心肌隐窝发生率与以往研究报告的发生率一致，尽管在日本人群中最常见的部位是左心室心尖。
