Kang Joonseo, Lee Kwon Woo, Chung Yeongu, Won Yusam, Hong Je Beom
Department of Neurosurgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Brain Tumor Res Treat. 2023 Oct;11(4):274-280. doi: 10.14791/btrt.2023.0029.
Ependymoma is a rare adult tumor that originates from ependymal cells of the central nervous system, primarily occurring in the cerebral ventricles or the central canal of the spinal cord. In this paper, we report a case of extensive leptomeningeal seeding of ependymoma of a 39-year-old male patient, in whom the tumor was found incidentally after head trauma. The MRI exhibited diffuse leptomeningeal infiltrative lesions along with bilateral multiple cerebral sulci, basal cisterns, cerebellopontine angle, cerebellar folia. It also showed multinodular enhancing T1 low T2 high signal intensity lesions along the whole spinal cord. After the tumor biopsy at right temporal lesion, pathologic diagnosis was classic ependymoma (WHO grade 2). The patient has undergone radiation therapy and chemotherapy, and is currently maintaining a stable condition two years after surgery. This report suggests that when considering the differential diagnosis of extensive lesions both in the intracranial and intraspinal space, ependymoma should also be considered.
室管膜瘤是一种罕见的成人肿瘤，起源于中枢神经系统的室管膜细胞，主要发生在脑室或脊髓中央管。在本文中，我们报告了一例39岁男性患者室管膜瘤广泛软脑膜播散的病例，该患者在头部外伤后偶然发现肿瘤。MRI显示沿双侧多个脑沟、脑池、桥小脑角、小脑叶片有弥漫性软脑膜浸润性病变。还显示沿整个脊髓有多结节强化的T1低T2高信号强度病变。在对右侧颞部病变进行肿瘤活检后，病理诊断为经典型室管膜瘤（世界卫生组织2级）。该患者已接受放疗和化疗，目前术后两年病情稳定。本报告提示，在考虑颅内和椎管内广泛病变的鉴别诊断时，也应考虑室管膜瘤。
