Ohhashi M, Usuda N, Sugenoya A, Adati W, Morimoto M, Nagata T, Iida F
Gan No Rinsho. 1986 Nov;32(14):1787-94.
The distribution pattern of fibronectin in human lung cancer tissues has been studied using the indirect immunoperoxidase technique. In adenocarcinoma fibronectin is observed in the basal side of cancer cells and tumor stroma. In squamous cell carcinoma, it is seen in the basal side of cancer cells, surface of cancer cells and tumor stroma. The difference between adenocarcinoma and squamous cell carcinoma in invasion and metastasis was investigated to have some relation to the distribution pattern of fibronectin.
利用间接免疫过氧化物酶技术研究了纤连蛋白在人肺癌组织中的分布模式。在腺癌中,纤连蛋白见于癌细胞的基底侧和肿瘤基质。在鳞状细胞癌中,纤连蛋白见于癌细胞的基底侧、癌细胞表面和肿瘤基质。研究了腺癌和鳞状细胞癌在侵袭和转移方面的差异,发现其与纤连蛋白的分布模式有一定关系。