Johnson R B
J Theor Biol. 1986 Sep 7;122(1):19-24. doi: 10.1016/s0022-5193(86)80222-3.
Theorists who make a priori generalizations about the tendency of host-parasite systems to co-evolve toward commensalism or increased parasitism err because they do not consider the empirical relation between host pathology and pathogen transmission. Natural selection should favor increased pathogen virulence in diseases where host pathology contributes to pathogen transmission and favor decreased virulence when pathology impedes transmission. This paper classifies important human diseases according to the contribution human pathology makes to pathogen transmission.
那些对宿主 - 寄生虫系统朝着共生或寄生虫增多方向共同进化的趋势进行先验概括的理论家是错误的，因为他们没有考虑宿主病理学与病原体传播之间的实证关系。在宿主病理学有助于病原体传播的疾病中，自然选择应有利于病原体毒力增强；而当病理学阻碍传播时，则有利于毒力降低。本文根据人类病理学对病原体传播的作用对重要的人类疾病进行了分类。
