From the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA.
Sex Transm Dis. 2024 Feb 1;51(2):85-89. doi: 10.1097/OLQ.0000000000001900. Epub 2023 Nov 11.
Current US syphilis screening focuses on men who have sex with men (MSM), because of the increased risk of infection in their sexual networks, and on pregnant people, because of complications associated with congenital syphilis. However, screening for men who have sex with women (MSW) who are at increased risk of syphilis is also recommended. Factors associated with syphilis testing and positivity were assessed among young, Black MSW.
Data from the Check It study-a seek, test, and treat study for chlamydia in New Orleans, LA, among Black MSW aged 15 to 26 years-were used. Survey data were used to elicit self-reported syphilis testing, self-reported testing results, and sociodemographic and behavioral factors associated with these 2 outcomes.
Per the Centers for Disease Control and Prevention, all men in the study were recommended for syphilis screening because of their age, race, and geographic location. Of the 1458 men included, 272 (18.7%) reported ever having been syphilis tested, 267 men reported their results, and 23 (8.6%) reported testing positive. In logistic regression, older age (odds ratio [OR], 1.21 per year older; P < 0.001), prior Chlamydia trachomatis , Neisseria gonorrhoeae , and/or HIV testing (OR, 50.32; P < 0.001), and younger age at sexual debut (0.90 per year older, P = 0.005) were significantly associated with prior syphilis testing. In addition, testing positive for C. trachomatis and/or N. gonorrhoeae during the study was significantly associated with a history of syphilis positivity (OR, 3.08; P = 0.031).
Although syphilis testing was associated with factors that might increase the risk of acquisition, only 19% of individuals meeting Centers for Disease Control and Prevention testing recommendations had ever been screened.
目前美国的梅毒筛查重点关注男男性行为者(MSM),因为他们的性网络中存在感染风险增加,以及孕妇,因为先天性梅毒相关并发症。然而,也建议对感染梅毒风险增加的女男性行为者(MSW)进行筛查。评估了感染梅毒风险增加的年轻黑人 MSW 中与梅毒检测和阳性相关的因素。
本研究数据来自新奥尔良的 Check It 研究,该研究是在 LA 对年龄在 15 至 26 岁之间的黑人 MSW 中进行的衣原体寻找、检测和治疗研究。使用调查数据来收集自我报告的梅毒检测、自我报告的检测结果以及与这两个结果相关的社会人口学和行为因素。
根据疾病预防控制中心的规定,由于年龄、种族和地理位置,所有研究中的男性都建议进行梅毒筛查。在 1458 名男性中,272 名(18.7%)报告曾接受过梅毒检测,267 名男性报告了检测结果,23 名(8.6%)报告检测结果阳性。在逻辑回归中,年龄较大(优势比[OR],每年增加 1.21;P < 0.001)、先前检测过沙眼衣原体、淋病奈瑟菌和/或 HIV(OR,50.32;P < 0.001)以及初次性行为年龄较小(每年增加 0.90 岁,P = 0.005)与先前梅毒检测显著相关。此外,在研究期间检测出沙眼衣原体和/或淋病奈瑟菌阳性与梅毒阳性史显著相关(OR,3.08;P = 0.031)。
尽管梅毒检测与可能增加感染风险的因素相关,但只有 19%符合疾病预防控制中心检测建议的个体接受过筛查。