体重过重对眼内压的影响：系统评价和荟萃分析。

Role of excessive weight in intraocular pressure: a systematic review and meta-analysis.

机构信息

Department of Ophthalmology, Hasanuddin University, Makassar, Indonesia.

Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

出版信息

BMJ Open Ophthalmol. 2023 Nov;8(1). doi: 10.1136/bmjophth-2023-001355.

DOI:10.1136/bmjophth-2023-001355

PMID:37963670

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10649692/

Abstract

OBJECTIVE

This systematic review and meta-analysis aimed to analyse the effect of excess body weight on intraocular pressure (IOP) values.

METHOD AND ANALYSIS

A literature search from PubMed, Medline and ScienceDirect Databases on 18 May 2023 was conducted by three reviewers, then filtered each study based on inclusion and exclusion criteria. For the quality assessment of included studies, the Newcastle-Ottawa Scale was adapted. Meta-analysis was performed using RevMan V.5.4 by entering the IOP values of each group to measure the mean difference.

RESULTS

From 2656 studies, there were 9 studies that matched the criteria and then were included to perform a quantitative meta-analysis. The results showed a mean difference of 0.93 (95% CI: 0.67 to 1.18) of the excessive weight group against the normal weight group. This suggests that there is a significant relationship between excess body weight and increasing values of IOP.

CONCLUSION

It can be concluded that excessive body weight tends to lead to higher IOP, which means that high IOP becomes a major risk factor for glaucoma.

摘要

目的

本系统评价和荟萃分析旨在分析超重对眼内压（IOP）值的影响。

方法和分析

三位评审员于 2023 年 5 月 18 日在 PubMed、Medline 和 ScienceDirect 数据库中进行了文献检索，然后根据纳入和排除标准筛选了每项研究。为了评估纳入研究的质量，采用了纽卡斯尔-渥太华量表。通过输入每个组的 IOP 值来测量平均值差异，使用 RevMan V.5.4 进行荟萃分析。