蜂蜜、芦荟和水胶体敷料对小鼠切除伤口愈合过程的影响。
The Effect of Honey, Aloe Vera, and Hydrocolloid Dressing on the Healing Process of Murine Excisional Wounds.
作者信息
Hernández-Rodríguez José Enrique, Martín-Barrasa José Luis, Aragón-Sánchez J, Monzón-Mayor Maximina, Pérez-Galván José Manuel, Saavedra-Santana Pedro, Romero-Alemán María Del Mar
机构信息
Department of Nursing, University of Las Palmas de Gran Canaria, University Institute for Biomedical and Health Research, Las Palmas de Gran Canaria, Las Palmas, Spain.
Dr. Negrin University Hospital Research Unit and University Institute for Animal Health, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Las Palmas, Spain.
出版信息
Int J Low Extrem Wounds. 2023 Nov 15:15347346231214597. doi: 10.1177/15347346231214597.
Chronic ulcers are a major health problem associated with high costs and a loss of quality of life. Because of this, the search for products that accelerate wound healing is a constant, given the need for alternatives that help to alleviate this serious health problem. We analyzed the efficacy of 2 natural products-honey and aloe vera-versus hydrocolloid (HC) dressings as a control group in healing full-thickness wounds. For this purpose, we performed full-thickness excisions of the skin, including the , in mice. We inserted a nitrile ring into the subcutaneous cellular tissue simulating the second-intention wound healing course. We found that aloe vera reduced the diameter of the wounds compared to honey ( < .001) and the control group ( < .001).
慢性溃疡是一个重大的健康问题，会带来高昂的成本和生活质量的下降。因此，鉴于需要有助于缓解这一严重健康问题的替代方法，寻找能够加速伤口愈合的产品一直是人们不断努力的方向。我们分析了两种天然产品——蜂蜜和芦荟——与水胶体（HC）敷料作为对照组在愈合全层伤口方面的疗效。为此，我们对小鼠进行了包括皮下组织在内的皮肤全层切除。我们在皮下细胞组织中插入一个腈环，模拟二期愈合伤口的过程。我们发现，与蜂蜜组（P < 0.001）和对照组（P < 0.001）相比，芦荟能减小伤口直径。
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