埃塞俄比亚东部公立医院中感染艾滋病病毒的女性的宫颈癌筛查接受情况及相关因素

Cervical cancer screening uptake and associated factors among Women Living with in public hospitals, eastern Ethiopia.

作者信息

Tesfaye Dagnachew, Weldegebreal Fitsum, Ayele Firayad, Dheresa Merga

机构信息

Student Clinic, Haramaya University, Haramaya, Oromia, Ethiopia.

School of Medical Laboratory Sciences, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.

出版信息

Front Oncol. 2023 Oct 27;13:1249151. doi: 10.3389/fonc.2023.1249151. eCollection 2023.

DOI:10.3389/fonc.2023.1249151

PMID:37965474

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10642187/

Abstract

BACKGROUND

Cervical cancer, the second leading cancer in Ethiopia women, is six times higher among women infected with the Human Immune Virus 1-infected women. Its screening provides protective advantages, and is linked to a decrease in the incidence of invasive cervical cancer and mortality. Although cancer screening has great advantages for early treatment and prevention of further complications, cervical cancer screening uptake is low among women in developing countries. Cervical cancer screening uptake among Women Living with Human Immunodeficiency Virus (WLHIV) is not well known in Eastern Ethiopia. Thus, we aimed to assess cervical cancer screening uptake and its associated factors among WLHIV in public hospitals in Harar, eastern Ethiopia.

METHODS

An institution-based cross-sectional study was carried out on 412 randomly selected HIV-positive women from March 20 to April 20, 2022. The results of the study were presented descriptively in percentages and analytically in odds ratio. Bivariate and multivariable logistic regression analyses were used to determine the presence and degree of association between dependent and independent variables. In the multivariable logistic analysis, a p-value of 0.05, and an adjusted odds ratio with a 95% confidence interval were considered to determine independent predictors for the uptake of cervical cancer screening.

RESULTS

Cervical cancer screening uptake among WLHIV was 57.5% (95% CI: 52.5, 62.9%). The uptake of cervical cancer screening was significantly associated with age between 20-29 years (AOR = 7.33; 95% CI: 1.98, 27.1), 40-49 years (AOR = 4.37; 95% CI: 1.48, 12.89), tertiary level of education (AOR = 0.197; 95% CI: 0.041, 0.946), good knowledge (AOR = 3.591; 95% CI: 2.123, 6.073), and monthly income of 2501(45.52 $) and above Ethiopian Birr (AOR = 0.389; 95% CI: 0.158, 0.959).

CONCLUSIONS

More than half of the participants had undergone cervical cancer screening. Age, marital status, educational status, monthly income, and awareness of cancer screening uptake were all factors related to cervical cancer screening. To maximize uptake, it is necessary to create specific counseling and education programs that target HIV-positive women.

摘要

背景

宫颈癌是埃塞俄比亚女性中第二大常见癌症，在感染人类免疫缺陷病毒1型的女性中发病率高出六倍。宫颈癌筛查具有保护作用，与浸润性宫颈癌发病率和死亡率的降低相关。尽管癌症筛查对早期治疗和预防进一步并发症有很大优势，但发展中国家女性的宫颈癌筛查率较低。在埃塞俄比亚东部，感染人类免疫缺陷病毒的女性（WLHIV）的宫颈癌筛查率尚不清楚。因此，我们旨在评估埃塞俄比亚东部哈拉尔市公立医院中WLHIV的宫颈癌筛查率及其相关因素。

方法

于2022年3月20日至4月20日对412名随机选择的HIV阳性女性进行了一项基于机构的横断面研究。研究结果以百分比形式进行描述性呈现，并以优势比进行分析。采用双变量和多变量逻辑回归分析来确定因变量和自变量之间关联的存在及程度。在多变量逻辑分析中，以p值为0.05以及具有95%置信区间的调整优势比来确定宫颈癌筛查接受情况的独立预测因素。

结果

WLHIV中的宫颈癌筛查率为57.5%（95%CI：52.5，62.9%）。宫颈癌筛查率与20 - 29岁（优势比=7.33；95%CI：1.98，27.1）、40 - 49岁（优势比=4.37；95%CI：1.48，12.89）的年龄、高等教育水平（优势比=0.197；95%CI：0.041，0.946）、良好的认知（优势比=3.591；95%CI：2.123，6.073）以及每月收入2501埃塞俄比亚比尔（45.52美元）及以上（优势比=0.389；95%CI：0.158，0.959）显著相关。