School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, China.
Xiangya Stomatological Hospital, Central South University, Changsha 410008, China.
Biomater Sci. 2023 Dec 19;12(1):92-107. doi: 10.1039/d3bm01151h.
Titanium (Ti) and its alloys are widely used in clinical practice. As they are not bioactive, hydroxyapatite (HA) is commonly used to modify them. This study offered a review of microwave-assisted synthesis of composites based on Ti and HA for dental implantation by exploring their interaction mechanisms with microwave and features of two main techniques, namely microwave coating and sintering, along with current challenges and potential solutions in the field. It was shown that microwave coating enables rapid deposition of HA, but suffers from problems such as uneven coating thickness, poor integrity and unstable composition of the products. They can be solved by creating interlayers, combining the spin coating technique, . Unlike microwave coating, microwave sintering can effectively modify the mechanical properties of the composites, despite the shortcomings of excessive elastic moduli and potential HA decomposition. These issues are expected to be addressed by adding alloying elements and employing appropriate materials as space holders and ion-doped HA for sintering.
钛(Ti)及其合金在临床实践中得到了广泛的应用。由于它们没有生物活性,因此通常使用羟基磷灰石(HA)对其进行改性。本研究通过探讨微波辅助合成基于 Ti 和 HA 的复合材料的相互作用机制及其两种主要技术(微波涂层和烧结)的特点,综述了用于牙科植入物的复合材料的微波辅助合成。同时还讨论了该领域目前的挑战和潜在解决方案。研究表明,微波涂层能够实现 HA 的快速沉积,但存在涂层厚度不均匀、完整性差以及产品成分不稳定等问题。通过创建中间层、结合旋涂技术可以解决这些问题。与微波涂层不同,微波烧结可以有效改善复合材料的力学性能,但存在弹性模量过高和潜在的 HA 分解等缺点。预计通过添加合金元素以及使用合适的材料作为空间占位剂和掺杂离子的 HA 进行烧结,可以解决这些问题。