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损伤控制外科在伴有感染性休克的牙源性颈坏死性筋膜炎治疗中的临床研究。

Clinical Study of Damage Control Surgery in the Management of Odontogenic Cervical Necrotizing Fasciitis with Septic Shock.

出版信息

Altern Ther Health Med. 2024 Mar;30(3):97-101.

PMID:37971435
Abstract

OBJECTIVE

To evaluate the clinical efficacy of damage control surgery (DCS) in the treatment of odontogenic cervical Necrotizing Fasciitis (CNF) complicated with septic shock.

METHODS

From January 2019 to January 2022, 8 cases with odontogenic cervical Necrotizing Fasciitis (CNF) complicated with septic shock were selected. According to the concept of damage control surgery (DCS), they were treated with incision and decompression, debridement and sealing vacuum suction (VSD) at the early stage, anti-shock, anti-infection, life support. At the later stage, the patients were treated by skin autograft combined with early rehabilitation.

RESULTS

In 8 cases, shock was corrected in a short time, lac decreased rapidly, infection index including white blood cell (WBC), C-reactive protein (CRP), thrombocytocrit (PCT) decreased rapidly, organ function including blood urea nitrogen (BUN), total bilirubin (Tbil), Aspartate aminotransferase (AST), alanine aminotransferase (ALT), albumin (Alb), creatine kinase (CK) was improved effectively, P < .05. The wounds of all the patients were effectively closed and cured. The average days of hospitalization were 21-42 days (27.00±3.20 days). No recurrence was found in the follow-up of 6 months.

CONCLUSION

Odontogenic cervical Necrotizing fasciitis with septic shock progresses rapidly. Damage control surgery can effectively control infection, correct shock and avoid further deterioration of organ function. This scheme has unique advantages, which can make the wound repaired in time and improve the success rate of treatment. It is worth popularizing in clinic.

摘要

目的

评价损伤控制性手术(DCS)治疗牙源性颈坏死性筋膜炎(CNF)并发感染性休克的临床疗效。

方法

选取 2019 年 1 月至 2022 年 1 月收治的 8 例牙源性颈坏死性筋膜炎(CNF)并发感染性休克患者,根据损伤控制性手术(DCS)理念,早期行切开减压、清创及负压封闭引流(VSD)、抗休克、抗感染、生命支持治疗,后期行皮片自体移植+早期康复治疗。

结果

8 例患者均在短时间内纠正休克,局部肿胀迅速消退,白细胞(WBC)、C 反应蛋白(CRP)、血小板压积(PCT)等感染指标迅速下降,血尿素氮(BUN)、总胆红素(Tbil)、天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、白蛋白(Alb)、肌酸激酶(CK)等器官功能指标均得到有效改善,差异均有统计学意义(P<0.05)。所有患者的创面均有效闭合治愈,平均住院时间 21~42 天,(27.00±3.20)天。随访 6 个月均无复发。

结论

牙源性颈坏死性筋膜炎并发感染性休克进展迅速,采用损伤控制性手术可有效控制感染、纠正休克,避免器官功能进一步恶化,该方案具有独特的优势,可及时修复创面,提高治疗成功率,值得临床推广。

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