Center for Pediatric Trauma Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States of America.
Center for Injury Research and Policy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States of America.
PLoS One. 2023 Nov 16;18(11):e0294279. doi: 10.1371/journal.pone.0294279. eCollection 2023.
The objective of this study was to determine the reduction in prescribed opioid pain dosage units to pediatric patients experiencing acute pain and to assess patient satisfaction with pain control 90-day post discharge following the 2017 Ohio opioid prescribing cap law.
The retrospective chart review included 960 pediatric (age 0-18 years) burn injury and knee arthroscopy patients treated between August 1, 2015-August 31, 2019. Prospectively, legal guardians completed a survey for a convenience sample of 50 patients. Opioid medications (days and morphine milligram equivalents (MMEs)/kg) prescribed at discharge before and after the Ohio law implementation were collected. Guardians reported experience and satisfaction with their child's opioid prescription at 90-days post discharge.
From pre-law to post-law, there was a significant decrease (p<0.001) within the burn and knee cohorts in the median days (1.7 to 1.0 and 5.0 to 3.8, respectively) and median total MMEs prescribed (15.0 to 2.5 and 150.0 to 90.0, respectively). An interrupted time series analysis revealed a statistically significant decrease in MMEs/kg and days prescribed at discharge when the 2017 Ohio opioid prescription law went into effect, with an abrupt level change. Prospectively, more than half of participants were satisfied (72% burn and 68% knee) with their pain control and felt they received the right amount of medication (84% burn and 56% knee). Inpatient opioid use was not changed pre- and post-law.
Discharge opioids prescribed for pediatric burn and knee arthroscopy procedures has decreased from 2015-2019. Caregivers varied greatly in their satisfaction with pain control and the amount of opioid prescribed.
本研究旨在确定在俄亥俄州 2017 年阿片类药物处方限制法实施后,接受急性疼痛治疗的儿科患者的处方阿片类药物疼痛剂量单位减少情况,并评估患者出院后 90 天的疼痛控制满意度。
回顾性图表审查纳入了 2015 年 8 月 1 日至 2019 年 8 月 31 日期间接受治疗的 960 名(年龄 0-18 岁)烧伤和膝关节镜检查的儿科患者。前瞻性地,合法监护人完成了一项方便抽样的 50 名患者的调查。收集了俄亥俄州法律实施前后出院时开具的阿片类药物(天数和吗啡毫克当量(MME)/kg)。监护人报告了出院后 90 天内其子女阿片类药物处方的经历和满意度。
从法律实施前到实施后,烧伤和膝关节镜两组患者的中位数天数(分别为 1.7 天至 1.0 天和 5.0 天至 3.8 天)和中位数总 MMEs 处方量(分别为 15.0 MME 至 2.5 MME 和 150.0 MME 至 90.0 MME)均显著减少(p<0.001)。中断时间序列分析显示,2017 年俄亥俄州阿片类药物处方限制法生效时,出院时 MMEs/kg 和处方天数呈统计学显著下降,且出现突然的水平变化。前瞻性地,超过一半的参与者对疼痛控制感到满意(烧伤组为 72%,膝关节组为 68%),并认为他们接受了适量的药物治疗(烧伤组为 84%,膝关节组为 56%)。住院期间的阿片类药物使用在法律实施前后没有变化。
2015-2019 年,儿科烧伤和膝关节镜手术的出院阿片类药物处方量有所减少。看护人对疼痛控制和阿片类药物处方量的满意度差异很大。