Chen Hongming, Lin Miao, Zhu Yanan, Zhang Dongwei, Chen Jingru, Wei Qingsong, Yuan Siqi, Liao Yibin, Chen Fuhai, Chen Yong, Lin Meijin, Fang Xin
College of Materials Science and Engineering, Fuzhou University, Fuzhou, 350116, P. R. China.
College of Chemistry, Fuzhou University, Fuzhou, 350116, P. R. China.
Small. 2024 Apr;20(14):e2307277. doi: 10.1002/smll.202307277. Epub 2023 Nov 16.
Organic scintillators with efficient X-ray excited luminescence are essential for medical diagnostics and security screening. However, achieving excellent organic scintillation materials is challenging due to low X-ray absorption coefficients and inferior radioluminescence (RL) intensity. Herein, supramolecular interactions are incorporated, particularly halogen bonding, into organic scintillators to enhance their radioluminescence properties. By introducing heavy atoms (X = Cl, Br, I) into 9,10-bis(4-pyridyl)anthracene (BPA), the formation of halogen bonding (BPA-X) enhances their X-ray absorption coefficient and restricts the molecular vibration and rotation, which boosts their RL intensity. The RL intensity of BPA-Cl and BPA-Br fluorochromes increased by over 2 and 6.3 times compared to BPA, respectively. Especially, BPA-Br exhibits an ultrafast decay time of 8.25 ns and low detection limits of 25.95 ± 2.49 nGy s. The flexible film constructed with BPA-Br exhibited excellent X-ray imaging capabilities. Furthermore, this approach is also applicable to organic phosphors. The formation of halogen bonding in bromophenyl-methylpyridinium iodide (PYI) led to a fourfold increase in RL intensity compared to bromophenyl-methyl-pyridinium (PY). It suggests that halogen bonding serves as a promising and effective molecular design strategy for the development of high-performance organic scintillator materials, presenting new opportunities for their applications in radiology and security screening.
具有高效X射线激发发光的有机闪烁体对于医学诊断和安全筛查至关重要。然而，由于X射线吸收系数低和放射oluminescence（RL）强度较差，实现优异的有机闪烁体材料具有挑战性。在此，将超分子相互作用，特别是卤键，引入有机闪烁体中以增强其放射发光性能。通过将重原子（X = Cl、Br、I）引入9,10-双（4-吡啶基）蒽（BPA）中，卤键（BPA-X）的形成增强了它们的X射线吸收系数并限制了分子振动和旋转，从而提高了它们的RL强度。与BPA相比，BPA-Cl和BPA-Br荧光染料的RL强度分别提高了2倍以上和6.3倍。特别是，BPA-Br表现出8.25 ns的超快衰减时间和25.95±2.49 nGy s的低检测限。用BPA-Br构建的柔性薄膜表现出优异的X射线成像能力。此外，这种方法也适用于有机磷光体。与溴苯基甲基吡啶（PY）相比，溴苯基甲基吡啶碘化物（PYI）中卤键的形成导致RL强度增加了四倍。这表明卤键作为一种有前途且有效的分子设计策略，用于开发高性能有机闪烁体材料，为其在放射学和安全筛查中的应用带来了新机遇。
