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甲状旁腺腺瘤的外科治疗结果

Outcomes of Surgical Management for Parathyroid Adenomas.

作者信息

Dhingani Gargi, Malik Akshat, Singh Vikram, Chaturvedi Harit, Nayyar Rohit

机构信息

Department Of Surgical Oncology, Max Superspeciality Hospital, Saket, New Delhi, 110017 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):3439-3442. doi: 10.1007/s12070-023-04006-7. Epub 2023 Jun 27.

Abstract

AIM

Descriptive analysis of patients undergoing parathyroid adenoma surgery at a tertiary care hospital.

METHODOLOGY

Patients with parathyroid adenoma operated from January 2016 to December 2020. Serum calcium and PTH were used to establish the diagnosis. Ultrasonography (USG) studies localized the adenoma. NIH criteria was used for decision regarding surgery. Patients were analyzed with regards to pre operative localization, biochemical monitoring and other outcomes.

RESULTS

Of the 15 eligible patients, all were symptomatic, with myalgia (34%) being the commonest symptom. Rome criteria confirmed the adequacy of the procedure by measuring intra operative drop in PTH. Average decrease in serum PTH level was 69.9% and serum calcium was 20.6% after excision of adenoma. The average size of excised adenoma was 2.5 cm. There were no post operative complications and all patients were normocalcemic on follow up.

CONCLUSION

Parathyroidectomy is a simple, safe and effective solution that reduces the morbidity of symptomatic primary hyperparathyroidism patients. Pre operative localization studies affirm the diagnosis and intra operative biochemical confirmation clinches the adequacy of resection.

摘要

目的

对一家三级护理医院接受甲状旁腺腺瘤手术的患者进行描述性分析。

方法

选取2016年1月至2020年12月期间接受甲状旁腺腺瘤手术的患者。采用血清钙和甲状旁腺激素(PTH)来确诊。通过超声检查(USG)对腺瘤进行定位。采用美国国立卫生研究院(NIH)标准来决定是否进行手术。对患者的术前定位、生化监测及其他结果进行分析。

结果

15例符合条件的患者均有症状,其中肌痛(34%)是最常见的症状。罗马标准通过测量术中PTH的下降情况来确认手术的充分性。腺瘤切除后,血清PTH水平平均下降69.9%,血清钙平均下降20.6%。切除的腺瘤平均大小为2.5厘米。术后无并发症,所有患者在随访时血钙正常。

结论

甲状旁腺切除术是一种简单、安全且有效的解决方法,可降低有症状的原发性甲状旁腺功能亢进患者的发病率。术前定位研究可确诊,术中生化确认可确保切除的充分性。

相似文献

1
Outcomes of Surgical Management for Parathyroid Adenomas.甲状旁腺腺瘤的外科治疗结果
Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):3439-3442. doi: 10.1007/s12070-023-04006-7. Epub 2023 Jun 27.

本文引用的文献

1
The EANM practice guidelines for parathyroid imaging.欧洲核医学学会甲状旁腺影像实践指南。
Eur J Nucl Med Mol Imaging. 2021 Aug;48(9):2801-2822. doi: 10.1007/s00259-021-05334-y. Epub 2021 Apr 10.

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