Sekar Raghul, Raja Kalaiarasi
Department of Otorhinolaryngology , Saveetha Medical College and Hospital , Chennai, India.
Department of Otorhinolaryngology, Jawaharlal Institute of Postgraduate Medical Education and Research(JIPMER), Puducherry, 605006 India.
Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):4106-4109. doi: 10.1007/s12070-023-04075-8. Epub 2023 Jul 23.
Langerhans cell histiocytosis (LCH) is a disease characterized by localized and generalized proliferation of the histiocytes. It is a locally aggressive condition. The clinical presentation is highly variable and can range from isolated, self-healing skin or bone lesions to life-threatening multisystem disease. It can present as a unifocal or multifocal disease. The majority are present in the head and neck region, but the involvement of Paranasal sinuses is rare. Here we describe a 64-years-old female who presented with a slow-growing left nasal mass for 1 year. Evaluation of the patient was suggestive of malignancy, but the biopsy report turned out to be Langerhans cell histiocytosis; subsequently left, total maxillectomy was done. We hereby present a unique case of LCH with isolated nose and paranasal sinus involvement.
朗格汉斯细胞组织细胞增多症（LCH）是一种以组织细胞局部和全身性增殖为特征的疾病。它是一种局部侵袭性疾病。临床表现高度多变，范围从孤立的、可自愈的皮肤或骨病变到危及生命的多系统疾病。它可表现为单灶性或多灶性疾病。大多数病例出现在头颈部区域，但鼻窦受累罕见。在此，我们描述一名64岁女性，她出现左侧鼻腔肿物缓慢生长1年。对该患者的评估提示为恶性，但活检报告结果为朗格汉斯细胞组织细胞增多症；随后进行了左侧全上颌骨切除术。我们在此呈现一例朗格汉斯细胞组织细胞增多症累及孤立鼻腔和鼻窦的独特病例。
