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糖尿病足溃疡患者的处方审核及用药依从性模式评估

Prescription auditing and assessment of medication adherence patterns in patients with diabetic foot ulcer.

作者信息

Varughese Reshma, H V Sowmya, K O Shwetha, Mathew Mintu

机构信息

Department of Pharmacy Practice, The Oxford College of Pharmacy, Hongasandra, Bangalore, Karnataka 560068 India.

出版信息

J Diabetes Metab Disord. 2023 Jun 13;22(2):1255-1261. doi: 10.1007/s40200-023-01241-1. eCollection 2023 Dec.

Abstract

BACKGROUND

Diabetic foot ulcer (DFU) is a serious infectious disease, which can be managed very well through proper medication, but if left untreated it may lead to amputation of the affected area leading to permanent immobility which will compromise the patient's quality of life.

OBJECTIVE

To carry out prescription auditing and to assess medication adherence patterns among DFU patients.

MATERIALS AND METHODS

A prospective interview-based study was carried out in the surgery department among inpatients aged above 18 years diagnosed with a DFU. A disease specific medication adherence questionnaire consisting of 15 questions was developed, validated and implemented among 65 patients. All the relevant data were analyzed and subjected to statistical analysis.

RESULTS

The majority (49.2%) of the population had an intermediate adherence pattern followed by high adherence (43%) during the first visit, later the reassessment after the counseling, reports a gradual increase in adherence pattern. Prescription auditing reveals the intensity of drug burden, on an average a prescription might carry 8 drugs and more than 95.3% of prescribed drugs were in injectable form.

CONCLUSION

This study highlights the depth of drug burden through prescription auditing and the necessity of proper patient counseling and educating the patient about the importance of medication adherence for limiting disease progression.

摘要

背景

糖尿病足溃疡(DFU)是一种严重的传染病,通过适当用药可得到很好的治疗,但如果不治疗,可能会导致受影响区域截肢,导致永久性行动不便,这将损害患者的生活质量。

目的

对糖尿病足溃疡患者进行处方审核并评估其用药依从性模式。

材料与方法

在外科对18岁以上诊断为糖尿病足溃疡的住院患者进行了一项基于访谈的前瞻性研究。开发了一份由15个问题组成的针对特定疾病的用药依从性问卷,在65名患者中进行了验证和实施。对所有相关数据进行分析并进行统计分析。

结果

大多数(49.2%)患者在首次就诊时依从性中等,其次是高依从性(43%),在咨询后的重新评估中,依从性模式逐渐增加。处方审核揭示了药物负担的强度,平均一张处方可能包含8种药物,超过95.3%的处方药为注射剂形式。

结论

本研究通过处方审核突出了药物负担的程度,以及适当的患者咨询和教育患者关于用药依从性对限制疾病进展的重要性的必要性。

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本文引用的文献

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Literature review on the management of diabetic foot ulcer.糖尿病足溃疡管理文献综述。
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