Labat-Robert J, Decaens C
Pathol Biol (Paris). 1979 Apr;27(4):241-7.
O-glycosylated glycoproteins are the main constituents of gastric mucus. They are responsible for its viscosity and for its gel-forming properties. Recent advances accomplished over the last years on its physical and chemical characterization are briefly reviewed. Many issues remain still unsettled concerning the modification of its structure and composition in diseases as well as details of its biosynthesis and its pharmacology.
O-糖基化糖蛋白是胃黏液的主要成分。它们决定了胃黏液的黏性及其形成凝胶的特性。本文简要综述了近年来在其物理和化学特性表征方面取得的进展。关于其在疾病中的结构和组成变化以及生物合成和药理学细节等许多问题仍未解决。