Hricak H, Stern J L, Fisher M R, Shapeero L G, Winkler M L, Lacey C G
Radiology. 1987 Feb;162(2):297-305. doi: 10.1148/radiology.162.2.3797641.
The potential of magnetic resonance (MR) imaging in the detection of endometrial carcinoma and in the assessment of its extent was evaluated prospectively in 51 patients clinically suspected of having the disease. MR imaging findings were compared with the results of surgical-pathologic staging and lymph node sampling following hysterectomy. Histologic findings showed 45 patients to have endometrial carcinoma, three to have no residual tumor after dilatation and curettage, and three to have adenomatous hyperplasia of the endometrium. MR imaging demonstrated an endometrial abnormality in 43 of the 51 patients (84%). Endometrial carcinoma could not be differentiated from adenomatous hyperplasia or blood clots. Therefore, MR imaging was not specific for tumor detection, and histologic diagnosis remains essential. The overall accuracy of MR imaging in staging endometrial carcinoma was 92%; its overall accuracy in demonstrating the depth of myometrial invasion was 82%. Demonstration of lymphadenopathy and adnexal or peritoneal metastases by MR imaging was suboptimal.
对51例临床怀疑患有子宫内膜癌的患者进行前瞻性评估，以确定磁共振（MR）成像在检测子宫内膜癌及其范围评估中的潜力。将MR成像结果与子宫切除术后手术病理分期和淋巴结采样结果进行比较。组织学检查结果显示，45例患者患有子宫内膜癌，3例在刮宫后无残留肿瘤，3例患有子宫内膜腺瘤样增生。MR成像显示51例患者中有43例（84%）存在子宫内膜异常。子宫内膜癌无法与腺瘤样增生或血凝块区分开来。因此，MR成像对肿瘤检测不具有特异性，组织学诊断仍然至关重要。MR成像对子宫内膜癌分期的总体准确率为92%；其显示肌层浸润深度的总体准确率为82%。MR成像对淋巴结病以及附件或腹膜转移的显示效果欠佳。
