Biondetti P R, Lee J K, Ling D, Catalona W J
Radiology. 1987 Feb;162(2):325-9. doi: 10.1148/radiology.162.2.3797644.
Magnetic resonance (MR) imaging studies were performed in 29 patients with clinical findings of stage B prostatic carcinoma with use of both T1 and T2-weighted spin echo sequences. MR imaging findings were correlated with surgical/pathologic results in 18 patients who underwent an operation. Periprostatic fat, periprostatic venous plexus, seminal vesicles, and lymph nodes were assessed from MR imaging studies. When each was assessed independently, the periprostatic fat signal had a sensitivity of 29%, specificity of 100%, and accuracy of 85% in detecting extracapsular tumor extension, whereas the periprostatic venous plexus had a sensitivity of 57%, specificity of 86%, and accuracy of 80%. MR imaging had a sensitivity of 50%, specificity of 97%, and accuracy of 89% for detecting seminal vesicular involvement. When all four anatomic features were taken into consideration, MR imaging had an accuracy of 89% (16 of 18 patients) in differentiating stage B from stage C or D disease (sensitivity 87%, specificity 90%). Our data indicate that MR imaging is a promising method for staging prostatic carcinoma.
对29例有B期前列腺癌临床表现的患者，采用T1加权和T2加权自旋回波序列进行了磁共振（MR）成像研究。对18例接受手术的患者，将MR成像结果与手术/病理结果进行了对比。通过MR成像研究对前列腺周围脂肪、前列腺周围静脉丛、精囊和淋巴结进行了评估。当对每个部位单独评估时，前列腺周围脂肪信号在检测包膜外肿瘤侵犯方面的敏感度为29%，特异度为100%，准确度为85%；而前列腺周围静脉丛的敏感度为57%，特异度为86%，准确度为80%。MR成像在检测精囊受累方面的敏感度为50%，特异度为97%，准确度为89%。当综合考虑所有四个解剖学特征时，MR成像在区分B期与C期或D期疾病方面的准确度为89%（18例患者中的16例）（敏感度87%，特异度90%）。我们的数据表明，MR成像对于前列腺癌分期是一种很有前景的方法。
