J Neurosurg Spine. 2023 Nov 17;40(2):152-161. doi: 10.3171/2023.9.SPINE23829. Print 2024 Feb 1.
The efficacy of anterior column realignment (ACR) remains relatively unclear, possibly because some safety concerns have limited its adoption and extensive evaluation. The authors aimed to study whether a minimally invasive surgery (MIS) triad consisting of ACR, lateral lumbar interbody fusion, and percutaneous pedicle screw fixation in a select group of adult spinal deformity (ASD) patients helps shorten fusion length without compromising clinical and radiographic outcomes over a minimum 2-year follow-up period.
A series of 61 ASD patients (mean age 72.8 years) with pelvic incidence (PI) - lumbar lordosis (LL) (PI-LL) mismatch > 10° underwent the short-segment MIS triad (mean fusion length 3.0 levels) as a single-stage operation with a mean operative time and estimated blood loss of 157 minutes and 127 mL, respectively. Exclusion criteria were 1) thoracic scoliosis as the main deformity, 2) thoracolumbar junction kyphosis > 25°, 3) ankylosed facet joints, and 4) previous spinal fusion surgery. Seven patients, who needed fusion to be extended to S1, underwent mini-open transforaminal lumbar interbody fusion at L5-S1.
The segmental disc angle at the ACR level more than quintupled, averaging from 2.9° preoperatively to 18.9° at the latest follow-up (p < 0.0001). LL, in turn, nearly doubled from 17.0° to 32.8° (p < 0.0001) and PI-LL decreased by nearly half from 28.8° to 13.2° (p < 0.0001). At the same time, other spinopelvic deformity parameters as well as Oswestry Disability Index (ODI) scores significantly improved. Patients were divided into two groups at the latest postoperative evaluation: 36 patients whose PI-LL improved to < 10° and 25 patients who maintained a PI-LL mismatch > 10°. Binary logistic regression revealed preoperative PI-LL mismatch as the only factor that significantly influenced this dichotomous separation postoperatively. Receiver operating characteristic curve analysis identified the critical preoperative mismatch of 26.4° with 68% sensitivity and 84% specificity. Despite this different radiographic consequence, the two groups had an equally successful clinical outcome with no significant difference in ODI scores.
As long as the ASD characteristics are consistent with the authors' exclusion criteria, the short-segment MIS triad served as an excellent surgical option in the patients with preoperative PI-LL mismatch < 26.4°, but the technique also worked well even in those with a mismatch > 26.4°, although ideal spinopelvic alignment targets were not necessarily achieved in these patients.
前路柱体重置(ACR)的疗效仍相对不明确,可能是因为一些安全问题限制了其应用和广泛评估。作者旨在研究在一组特定的成人脊柱畸形(ASD)患者中,由 ACR、侧方腰椎椎间融合和经皮椎弓根螺钉固定组成的微创手术三联疗法是否有助于缩短融合长度,同时在至少 2 年的随访期内不影响临床和影像学结果。
一组 61 例 ASD 患者(平均年龄 72.8 岁)存在骨盆入射角(PI)-腰椎前凸(LL)(PI-LL)不匹配 > 10°,接受了单阶段微创手术三联疗法(平均融合长度 3.0 个节段),手术时间和估计失血量分别为 157 分钟和 127 毫升。排除标准为 1)胸椎侧凸为主要畸形,2)胸腰椎交界处后凸 > 25°,3)关节突关节融合,4)既往脊柱融合手术。7 例需要融合至 S1 的患者在 L5-S1 行微创经椎间孔腰椎间融合术。
ACR 水平的节段性椎间盘角度增加了五倍以上,平均从术前的 2.9°增加到末次随访时的 18.9°(p < 0.0001)。同时,LL 从 17.0°增加到 32.8°(p < 0.0001),PI-LL 减少了近一半,从 28.8°减少到 13.2°(p < 0.0001)。与此同时,其他脊柱骨盆畸形参数和 Oswestry 残疾指数(ODI)评分也显著改善。患者在末次术后评估时分为两组:36 例 PI-LL 改善至 < 10°,25 例 PI-LL 不匹配 > 10°。二元逻辑回归显示术前 PI-LL 不匹配是术后这种二分法分离的唯一显著影响因素。受试者工作特征曲线分析确定了临界术前不匹配为 26.4°,具有 68%的敏感性和 84%的特异性。尽管存在这种不同的影像学结果,但两组的临床结果同样成功,ODI 评分无显著差异。
只要 ASD 特征符合作者的排除标准,短节段微创手术三联疗法是术前 PI-LL 不匹配 < 26.4°患者的优秀手术选择,但该技术在不匹配 > 26.4°的患者中也能很好地发挥作用,尽管这些患者不一定达到理想的脊柱骨盆对线目标。