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下胸椎与上腰椎作为上固定椎在成人脊柱畸形微创矫正中的影响。

The impact of lower thoracic versus upper lumbar upper instrumented vertebra in minimally invasive correction of adult spinal deformity.

作者信息

Eastlack Robert K, Kumar Jay I, Mundis Gregory M, Nunley Pierce D, Uribe Juan S, Park Paul J, Tran Stacie, Wang Michael Y, Than Khoi D, Okonkwo David O, Kanter Adam S, Anand Neel, Fessler Richard G, Fu Kai-Ming G, Chou Dean, Mummaneni Praveen V

机构信息

1Department of Orthopedic Surgery, Scripps Clinic, La Jolla, California.

2Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida.

出版信息

J Neurosurg Spine. 2025 Jan 10;42(4):462-469. doi: 10.3171/2024.8.SPINE231335. Print 2025 Apr 1.

Abstract

OBJECTIVE

The goal of this study was to compare the impact of using a lower thoracic (LT) versus upper lumbar (UL) level as the upper instrumented vertebra (UIV) on clinical and radiographic outcomes following minimally invasive surgery for adult spinal deformity.

METHODS

A multicenter retrospective study design was used. Inclusion criteria were age ≥ 18 years, and one of the following: coronal Cobb angle > 20°, sagittal vertical axis > 50 mm, pelvic tilt > 20°, pelvic incidence-lumbar lordosis mismatch > 10°. Patients were treated with circumferential or hybrid minimally invasive techniques at ≥ 3 spinal levels and had a 2-year minimum follow-up. They were then divided into 2 groups depending on whether the UIV was in the UL region, defined as a UIV location of L1-2, or the LT region, defined as T10-12.

RESULTS

A total of 114 of 223 patients met the inclusion criteria (68 LT and 46 UL). The UL group was older (67.5 vs 62.3 years; p = 0.015). Preoperative spinopelvic parameters were similar, except for sacral slope, which was higher in the UL group (30.5° vs 26.5°; p < 0.001). The percentage of patients with fixation crossing the lumbosacral junction was also similar (70.6% vs 67.4%; p = 0.717). Postoperative lumbar lordosis (42.5° vs 35.5°; p = 0.01) and change in coronal Cobb angle (-23.2° vs -9.6°; p < 0.001) were greater in the LT group, but other changes in postoperative spinopelvic parameters and changes in health-related quality-of-life scores were similar between groups. Reoperation rates were lower in the UL group (17.4% vs 36.8%; p = 0.025), largely associated with fewer radiographic failures (UL = 10.9% vs LT = 26.5%; p = 0.042); however, overall complication rates were not significantly different (UL = 43.5% vs LT = 60.3%; p = 0.077).

CONCLUSIONS

Selecting a UL vertebra for UIV in minimally invasive surgical correction of adult spinal deformity results in lower reoperation rates compared to extending fixation to the LT region. This choice also correlates with shorter operating room times and reduced estimated blood loss. Although extending fixation to the LT region is associated with slightly greater lumbar lordosis and a greater change in the coronal Cobb angle, clinical outcomes were similar between the LT and UL groups for UIV.

摘要

目的

本研究的目的是比较在成人脊柱畸形微创手术中,将下胸椎(LT)与上腰椎(UL)水平作为上固定椎(UIV)对临床和影像学结果的影响。

方法

采用多中心回顾性研究设计。纳入标准为年龄≥18岁,且符合以下条件之一:冠状面Cobb角>20°、矢状垂直轴>50mm、骨盆倾斜>20°、骨盆入射角-腰椎前凸失配>10°。患者采用环形或混合微创技术在≥3个脊柱节段进行治疗,并至少随访2年。然后根据UIV是位于UL区域(定义为L1-2的UIV位置)还是LT区域(定义为T10-12)将他们分为2组。

结果

223例患者中有114例符合纳入标准(68例LT组和46例UL组)。UL组年龄更大(67.5岁对62.3岁;p = 0.015)。术前脊柱骨盆参数相似,但UL组的骶骨斜率更高(30.5°对26.5°;p < 0.001)。固定跨越腰骶关节的患者百分比也相似(70.6%对67.4%;p = 0.717)。LT组术后腰椎前凸(42.5°对35.5°;p = 0.01)和冠状面Cobb角变化(-23.2°对-9.6°;p < 0.001)更大,但术后脊柱骨盆参数的其他变化以及健康相关生活质量评分的变化在两组之间相似。UL组的再次手术率较低(17.4%对36.8%;p = 0.025),主要与影像学失败较少有关(UL组 = 10.9%对LT组 = 26.5%;p = 0.042);然而,总体并发症发生率无显著差异(UL组 = 43.5%对LT组 = 60.3%;p = 0.077)。

结论

在成人脊柱畸形的微创矫正中,选择UL椎体作为UIV与将固定延伸至LT区域相比,再次手术率更低。这种选择还与更短的手术时间和更少的估计失血量相关。尽管将固定延伸至LT区域与稍大的腰椎前凸和更大的冠状面Cobb角变化相关,但LT组和UL组在UIV方面的临床结果相似。

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