Department of Physiology, Faculty of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey.
Department of Neurology, Faculty of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey.
Sleep Med. 2023 Dec;112:352-358. doi: 10.1016/j.sleep.2023.11.003. Epub 2023 Nov 7.
Obstructive sleep apnea (OSA) is a frequently observed and remarkably incapacitating disorder worldwide. As a multisystem disorder, OSA has been linked to a plethora of clinical parameters though physical parameters like muscle strength have been scantily studied. Hand grip strength (HGS) is a practical marker of physical function that has been associated with mortality and an array of clinical outcomes as well as physiological parameters like sleep duration. A few seminal studies have observed no link between HGS and OSA severity while no studies evaluated the relationship between objectively determined sleep duration and HGS in OSA.
The present study aimed to evaluate the HGS indices among both OSA severity groups and objectively determined sleep duration groups in OSA.
111 treatment-naïve mostly middle-aged individuals with OSA (86 males) were recruited in a tertiary sleep center. Three OSA severity groups were determined by the Apnea-Hypopnea Index while three sleep duration groups were objectively determined by Total Sleep Time (TST). Dominant and non-dominant maximum and average HGS were calculated using a digital hand dynamometer.
Short-sleeper individuals with OSA were found to have lower HGS indices than intermediate or sufficient sleepers with OSA while no differences in HGS indices among OSA severity groups were observed. All HGS indices correlated with TST.
Future insights can be gleaned from the present results regarding the conceivably transdiagnostic relationship between sleep duration and HGS as well as the potential use of HGS as a marker in OSA.
阻塞性睡眠呼吸暂停（OSA）是一种在全球范围内广泛观察到的、严重致残的疾病。作为一种多系统疾病，OSA 与许多临床参数有关，尽管肌肉力量等身体参数的研究很少。握力（HGS）是身体功能的一个实用指标，它与死亡率以及一系列临床结果以及生理参数（如睡眠时间）有关。一些开创性的研究观察到 HGS 与 OSA 严重程度之间没有联系，而没有研究评估 OSA 中客观确定的睡眠时间与 HGS 之间的关系。
本研究旨在评估 OSA 严重程度组和 OSA 客观确定的睡眠时间组的 HGS 指数。
在一家三级睡眠中心招募了 111 名未经治疗的、主要为中年的 OSA 患者（86 名男性）。通过呼吸暂停-低通气指数确定三个 OSA 严重程度组，通过总睡眠时间（TST）客观确定三个睡眠时间组。使用数字握力计计算优势和非优势的最大和平均 HGS。
与 OSA 中睡眠时间充足或中等的患者相比，OSA 中短睡者的 HGS 指数较低，而 OSA 严重程度组之间的 HGS 指数没有差异。所有 HGS 指数均与 TST 相关。
从目前的结果中可以了解到关于睡眠持续时间和 HGS 之间潜在的跨诊断关系，以及 HGS 作为 OSA 标志物的潜在用途。
