Chow C P, Wong L Y, Poon C Y C, Yiu B P H, Wong T P S, Wong M, Yam K Y, Ngai S P C
Child Assessment Service, Department of Health, Hong Kong SAR, China.
Department of Neurosurgery, Tuen Mun Hospital, Hospital Authority, Hong Kong SAR, China.
Childs Nerv Syst. 2024 Mar;40(3):873-880. doi: 10.1007/s00381-023-06213-7. Epub 2023 Nov 18.
This study examines long-term benefit on functional outcomes and quality of life after selective dorsal rhizotomy (SDR) in children with spastic diplegia in Hong Kong.
This is a case control study. Individuals with spastic diplegia who were at 6 to 12 years post-SDR were recruited. Age, gender, cognition, and Gross Motor Function Classification System level-matched individuals with spastic diplegia who had not undergone SDR were recruited as controls. Outcome measures included physical level, functional level, physiological level, and quality of life. All data were compared by independent t-test.
Individuals post-SDR (n = 15) demonstrated a significantly better range of ankle dorsiflexion in knee extension by - 5.7 ± 10.9° than the control group (n = 12). No other significant differences were observed.
SDR is a safe, one-off procedure and provides long-term reduction in spasticity with no major complications. With the heterogeneity, we did not demonstrate between-group differences in long-term functional outcomes.
本研究探讨香港痉挛性双瘫患儿选择性背根切断术(SDR)后对功能结局和生活质量的长期益处。
这是一项病例对照研究。招募SDR术后6至12年的痉挛性双瘫患者。年龄、性别、认知以及粗大运动功能分类系统水平相匹配的未接受SDR的痉挛性双瘫患者作为对照。结局指标包括身体水平、功能水平、生理水平和生活质量。所有数据采用独立t检验进行比较。
SDR术后患者(n = 15)在膝关节伸展时踝关节背屈范围比对照组(n = 12)显著改善-5.7±10.9°。未观察到其他显著差异。
SDR是一种安全的一次性手术,可长期减轻痉挛且无重大并发症。鉴于存在异质性,我们未证明两组在长期功能结局上存在差异。