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三尖瓣反流和右心衰竭:影像学在定义病理生理学、临床表现和新的治疗策略中的作用。

Tricuspid Regurgitation and Right Heart Failure: The Role of Imaging in Defining Pathophysiology, Presentation, and Novel Management Strategies.

机构信息

Division of Cardiology, Department of Medicine, Columbia University Medical Center/ New York Presbyterian Hospital, 177 Fort Washington Avenue, Room 5C-501, New York, NY 10032, USA.

Division of Cardiology, Department of Medicine, Columbia University Medical Center/ New York Presbyterian Hospital, 177 Fort Washington Avenue, Room 5C-501, New York, NY 10032, USA.

出版信息

Interv Cardiol Clin. 2024 Jan;13(1):81-99. doi: 10.1016/j.iccl.2023.09.003.

Abstract

During the last few years, there has been a substantial shift in efforts to understand and manage secondary or functional tricuspid regurgitation (TR) given its prevalence, adverse prognostic impact, and symptom burden associated with progressive right heart failure. Understanding the pathophysiology of TR and right heart failure is crucial for determining the best treatment strategy and improving outcomes. In this article, we review the complex relationship between right heart structural and hemodynamic changes that drive the pathophysiology of secondary TR and discuss the role of multimodality imaging in the diagnosis, management, and determination of outcomes.

摘要

在过去的几年中,人们对继发性或功能性三尖瓣反流(TR)的理解和管理投入了大量的努力,因为它的普遍性、对预后的不利影响以及与右心衰竭进展相关的症状负担。了解 TR 和右心衰竭的病理生理学对于确定最佳治疗策略和改善预后至关重要。在本文中,我们回顾了驱动继发性 TR 病理生理学的右心结构和血流动力学变化之间的复杂关系,并讨论了多模态成像在诊断、管理和确定结局中的作用。

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