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胰腺十二指肠切除术后预防胃排空延迟的手术技术。

Surgical techniques to prevent delayed gastric emptying after pancreaticoduodenectomy.

机构信息

Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, the First Hospital of Jilin University, Changchun 130021, China.

Department of Dental Implantology, Hospital of Stomatology, Jilin University, Changchun 130021, China.

出版信息

Hepatobiliary Pancreat Dis Int. 2024 Oct;23(5):449-457. doi: 10.1016/j.hbpd.2023.11.001. Epub 2023 Nov 7.

Abstract

BACKGROUND

Delayed gastric emptying (DGE) is one of the most common complications after pancreaticoduodenectomy (PD). DGE represents impaired gastric motility without significant mechanical obstruction and is associated with an increased length of hospital stay, increased healthcare costs, and a high readmission rate. We reviewed published studies on various technical modifications to reduce the incidence of DGE.

DATA SOURCES

Studies were identified by searching PubMed for relevant articles published up to December 2022. The following search terms were used: "pancreaticoduodenectomy", "pancreaticojejunostomy", "pancreaticogastrostomy", "gastric emptying", "gastroparesis" and "postoperative complications". The search was limited to English publications. Additional articles were identified by a manual search of references from key articles.

RESULTS

In recent years, various surgical procedures and techniques have been explored to reduce the incidence of DGE. Pyloric resection, Billroth II reconstruction, Braun's enteroenterostomy, and antecolic reconstruction may be associated with a decreased incidence of DGE, but more high-powered studies are needed in the future. Neither laparoscopic nor robotic surgery has demonstrated superiority in preventing DGE, and the use of staplers is controversial regarding whether they can reduce the incidence of DGE.

CONCLUSIONS

Despite many innovations in surgical techniques, there is no surgical procedure that is superior to others to reduce DGE. Further larger prospective randomized studies are needed.

摘要

背景

延迟性胃排空(DGE)是胰十二指肠切除术(PD)后最常见的并发症之一。DGE 代表胃动力受损而无明显机械梗阻,并与住院时间延长、医疗费用增加和高再入院率相关。我们回顾了已发表的关于各种技术改良以降低 DGE 发生率的研究。

资料来源

通过在 PubMed 上搜索截至 2022 年 12 月发表的相关文章,确定了研究。使用了以下搜索词:“胰十二指肠切除术”、“胰肠吻合术”、“胰胃吻合术”、“胃排空”、“胃轻瘫”和“术后并发症”。搜索仅限于英文出版物。通过对关键文章的参考文献进行手动搜索,还确定了其他文章。

结果

近年来,已经探索了各种手术程序和技术来降低 DGE 的发生率。幽门切除术、Billroth II 重建、Braun 肠肠吻合术和结肠前重建可能与 DGE 发生率降低相关,但未来需要更多的高影响力研究。腹腔镜或机器人手术在预防 DGE 方面均未显示出优势,吻合器的使用在是否可以降低 DGE 发生率方面存在争议。

结论

尽管在手术技术方面有许多创新,但没有一种手术程序可以优于其他手术来降低 DGE。需要进一步进行更大规模的前瞻性随机研究。

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