Membrane Research Laboratory, Department of Chemical Engineering, National Institute of Technology, Tiruchirappalli 620 015, Tamil Nadu, India.
Membrane Research Laboratory, Department of Chemical Engineering, National Institute of Technology, Tiruchirappalli 620 015, Tamil Nadu, India.
Int J Biol Macromol. 2024 Jan;256(Pt 1):128255. doi: 10.1016/j.ijbiomac.2023.128255. Epub 2023 Nov 18.
β-glucans are soluble fibers found in cereal compounds, including barley, oats etc., as an active component. They are used as a dietary fiber to treat cholesterol, diabetes and cardiovascular diseases. These polysaccharides are important because they can provide many therapeutic benefits related to their biological activity in human like inhibiting tumour growth, anti-inflammatory action, etc. All these activities were usually attached to their molecular weight, structure and degree of branching. The present manuscript reviews the background of β-glucan, its characterization techniques, the possible ways to extract β-glucan and mainly focuses on membrane-based purification techniques. The β-glucan separation methods using polymeric membranes, their operational characteristics, purification methods which may yield pure or crude β-glucan and structural analysis methods were also discussed. Future direction in research and development related to β-glucan recovery from cereal were also offered.
β-葡聚糖是谷物化合物中发现的可溶性纤维，包括大麦、燕麦等，作为一种活性成分。它们被用作膳食纤维来治疗胆固醇、糖尿病和心血管疾病。这些多糖很重要，因为它们可以提供许多与生物活性相关的治疗益处，如抑制肿瘤生长、抗炎作用等。所有这些活动通常与它们的分子量、结构和分支度有关。本文综述了β-葡聚糖的背景、其特性化技术、可能的提取β-葡聚糖的方法，主要集中在基于膜的纯化技术上。还讨论了使用聚合物膜的β-葡聚糖分离方法、它们的操作特性、可能产生纯或粗β-葡聚糖的纯化方法以及结构分析方法。还提供了谷物中β-葡聚糖回收的相关研究和开发的未来方向。
