Institute of Health Services Research, Yonsei University, Seoul, Republic of Korea.
Department of Preventive Medicine, Eulji University College of Medicine, Daejun, Republic of Korea.
Laryngoscope. 2024 May;134(5):2372-2376. doi: 10.1002/lary.31186. Epub 2023 Nov 21.
This study investigated the association between sudden sensorineural hearing loss (SSNHL) and the risk of cardio-cerebrovascular disease (CCVD) among older adults in South Korea.
Data from 38,426 patients in the Korean National Health Insurance Service-Senior Cohort from 2002 to 2019 were collected. The risk of CCVD includes both stroke and acute myocardial infarction. Propensity score matching (1:1) was used to identify pairs of individuals with and without SSNHL (n = 19,213 for cases and controls). Cox proportional hazards regression models were used to analyze the associations between variables.
Patients with SSNHL had a higher risk of CCVD (hazard ratio [HR] = 1.17, 95% confidence interval [CI] = 1.11-1.24) compared to those without. The risk of CCVD was higher among those who experienced a stroke than those who did not (HR = 1.17 95% CI = 1.10-1.25). Compared to their matched controls, patients with SSNHL were 1.69 times (HR = 1.69 CI = 1.46-1.94) more likely to have CCVD during the first 12 months of the follow-up period.
Older patients with SSNHL are at an increased risk of CCVD. Hence, a more attentive approach featuring aggressive monitoring of patients with SSNHL is required to lessen their risk of CCVD.
3 Laryngoscope, 134:2372-2376, 2024.
本研究旨在探讨韩国老年人突发性聋（SSNHL）与心脑血管疾病（CCVD）风险之间的关系。
收集了 2002 年至 2019 年韩国国民健康保险服务-老年人队列中 38426 名患者的数据。CCVD 的风险包括中风和急性心肌梗死。采用倾向评分匹配（1:1）对有和无 SSNHL 的个体进行配对（病例和对照组各 19213 人）。采用 Cox 比例风险回归模型分析变量之间的关系。
与无 SSNHL 的患者相比，患有 SSNHL 的患者发生 CCVD 的风险更高（风险比 [HR] = 1.17，95%置信区间 [CI] = 1.11-1.24）。与未发生中风的患者相比，发生中风的患者发生 CCVD 的风险更高（HR = 1.17 95% CI = 1.10-1.25）。与匹配的对照组相比，在随访的前 12 个月内，患有 SSNHL 的患者发生 CCVD 的风险增加了 1.69 倍（HR = 1.69 CI = 1.46-1.94）。
患有 SSNHL 的老年患者发生 CCVD 的风险增加。因此，需要对患有 SSNHL 的患者采取更积极的监测方法，以降低其发生 CCVD 的风险。
3 级。喉镜，134:2372-2376，2024。
