突发性聋与心脑血管疾病风险的相关性。

Association between Sudden Sensorineural Hearing Loss and the Risk of Cardio Cerebrovascular Disease.

机构信息

Institute of Health Services Research, Yonsei University, Seoul, Republic of Korea.

Department of Preventive Medicine, Eulji University College of Medicine, Daejun, Republic of Korea.

出版信息

Laryngoscope. 2024 May;134(5):2372-2376. doi: 10.1002/lary.31186. Epub 2023 Nov 21.

DOI:10.1002/lary.31186

PMID:37987243

Abstract

OBJECTIVES

This study investigated the association between sudden sensorineural hearing loss (SSNHL) and the risk of cardio-cerebrovascular disease (CCVD) among older adults in South Korea.

METHODS

Data from 38,426 patients in the Korean National Health Insurance Service-Senior Cohort from 2002 to 2019 were collected. The risk of CCVD includes both stroke and acute myocardial infarction. Propensity score matching (1:1) was used to identify pairs of individuals with and without SSNHL (n = 19,213 for cases and controls). Cox proportional hazards regression models were used to analyze the associations between variables.

RESULTS

Patients with SSNHL had a higher risk of CCVD (hazard ratio [HR] = 1.17, 95% confidence interval [CI] = 1.11-1.24) compared to those without. The risk of CCVD was higher among those who experienced a stroke than those who did not (HR = 1.17 95% CI = 1.10-1.25). Compared to their matched controls, patients with SSNHL were 1.69 times (HR = 1.69 CI = 1.46-1.94) more likely to have CCVD during the first 12 months of the follow-up period.

CONCLUSION

Older patients with SSNHL are at an increased risk of CCVD. Hence, a more attentive approach featuring aggressive monitoring of patients with SSNHL is required to lessen their risk of CCVD.

LEVEL OF EVIDENCE

3 Laryngoscope, 134:2372-2376, 2024.

摘要

目的

本研究旨在探讨韩国老年人突发性聋（SSNHL）与心脑血管疾病（CCVD）风险之间的关系。

方法

收集了 2002 年至 2019 年韩国国民健康保险服务-老年人队列中 38426 名患者的数据。CCVD 的风险包括中风和急性心肌梗死。采用倾向评分匹配（1:1）对有和无 SSNHL 的个体进行配对（病例和对照组各 19213 人）。采用 Cox 比例风险回归模型分析变量之间的关系。

结果

与无 SSNHL 的患者相比，患有 SSNHL 的患者发生 CCVD 的风险更高（风险比 [HR] = 1.17，95%置信区间 [CI] = 1.11-1.24）。与未发生中风的患者相比，发生中风的患者发生 CCVD 的风险更高（HR = 1.17 95% CI = 1.10-1.25）。与匹配的对照组相比，在随访的前 12 个月内，患有 SSNHL 的患者发生 CCVD 的风险增加了 1.69 倍（HR = 1.69 CI = 1.46-1.94）。