四氧化锇导致的皮肤变色。
Dermal discoloration due to osmium tetroxide.
机构信息
Department of Dermatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
出版信息
Clin Toxicol (Phila). 2023 Nov;61(11):1004-1005. doi: 10.1080/15563650.2023.2281253. Epub 2023 Dec 19.
INTRODUCTION
Osmium tetroxide is a strong oxidizing agent. After dermal exposure to osmium tetroxide, skin discoloration and red papules can occur. We describe a patient with skin discoloration due to osmium tetroxide.
CASE SUMMARY
A 25-year-old postgraduate student unintentionally exposed his hand to osmium tetroxide while working in a laboratory setting. After immediate washing, he sought medical care due to left middle finger discoloration. He reported no discomfort in the affected area. Thorough water rinsing was continued, and corticosteroid ointment was applied.
IMAGES
Our patient developed dark brown pigmentation on the ventral side of the left middle finger. The pigmentation disappeared one week later.
CONCLUSION
Osmium tetroxide may induce dark brown skin discoloration.
简介
四氧化锇是一种强氧化剂。皮肤接触四氧化锇后，可能会出现皮肤变色和红色丘疹。我们描述了一位因四氧化锇导致皮肤变色的患者。
病例总结
一名 25 岁的研究生在实验室工作时，不慎将手暴露于四氧化锇中。在立即清洗后，由于左手中指变色，他寻求医疗救助。他报告说受影响区域没有不适。持续进行彻底的水洗，并涂抹了皮质类固醇软膏。
图像
我们的患者左手中指腹出现深褐色色素沉着。色素沉着在一周后消失。
结论
四氧化锇可能导致深褐色皮肤变色。
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