脱蛋白牛骨矿物质覆盖胶原蛋白膜与纤维蛋白胶在牙槽嵴保存中放射学比较：一项回顾性研究。
Radiographic comparison of atelocollagen versus deproteinized bovine bone minerals covered with a collagen membrane in alveolar ridge preservation: a retrospective study.
机构信息
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Department of Implantology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
出版信息
BMC Oral Health. 2023 Nov 21;23(1):901. doi: 10.1186/s12903-023-03647-y.
BACKGROUND
Atelocollagen (AC) is a low-immunogenic collagen derivative with longer degradation time, which can be a suitable material for alveolar ridge preservation (ARP). However, there are few human studies on AC using for ARP. This research aims to radiographically evaluate the efficacy of AC in comparison to deproteinized bovine bone minerals covered with a collagen membrane (DBBM/CM) in ARP.
METHODS
Medical records in the Implantology Department of the Hospital of Stomatology of Wuhan University were screened for patients who received flapless ARP using either AC or DBBM/CM. A total of 58 patients were included in this retrospective study. 28 patients were treated with AC, while 30 patients were used DBBM/CM. Cone-beam computed tomography (CBCT) scans were taken before extraction and after 6 months of healing. To assess the dimensional change of the extraction sockets, the scanning data were output and transferred to the digital software to measure horizontal bone width change, vertical bone height change and bone volume change in region of interest. To evaluate the bone quality of healed sockets, the bone density of virtual implants was evaluated.
RESULTS
The horizontal bone width changes at all five different levels showed no significant difference between the two groups. The largest horizontal bone width decrement in both groups occurred at the crest of ridge, which decreased 3.71 ± 1.67 mm in AC group and 3.53 ± 1.51 mm in DBBM/CM group (p = 0.68). At the central buccal aspect, the ridge height reduced 0.10 ± 1.30 mm in AC group, while increased 0.77 ± 2.43 mm in DBBM/CM group (p = 0.10). The vertical bone height differences between two groups showed no statistical significance. The percentages of volume absorption in AC group and DBBM/CM group were 12.37%±6.09% and 14.54%±11.21%, respectively. No significant difference in volume absorption was found (p = 0.36). The average bone density around virtual implants in AC group (649.41 ± 184.71 HU) was significantly lower than that in DBBM/CM group (985.23 ± 207.85 HU) (p < 0.001).
CONCLUSIONS
ARP with AC had a similar effect on limiting the dimensional alteration of alveolar ridge, when radiographically compared with DBBM/CM.
背景
脱细胞真皮（AC）是一种免疫原性较低的胶原衍生物，其降解时间较长，可作为牙槽嵴保存（ARP）的合适材料。然而，目前关于 AC 用于 ARP 的人体研究较少。本研究旨在通过影像学评估 AC 与包被胶原膜的脱蛋白牛骨矿物质（DBBM/CM）在 ARP 中的疗效。
方法
筛选武汉大学口腔医院种植科使用 AC 或 DBBM/CM 进行无瓣 ARP 的患者的病历。共有 58 例患者纳入本回顾性研究。28 例患者接受 AC 治疗，30 例患者接受 DBBM/CM 治疗。在拔牙前和愈合后 6 个月时进行锥形束 CT（CBCT）扫描。为了评估拔牙窝的形态变化，将扫描数据输出并传输到数字软件中，以测量感兴趣区域的水平骨宽度变化、垂直骨高度变化和骨体积变化。为了评估愈合窝的骨质量，评估了虚拟植入物的骨密度。
结果
两组患者在五个不同水平的水平骨宽度变化均无显著差异。两组中最大的水平骨宽度减少均发生在牙槽嵴顶，AC 组减少 3.71±1.67mm，DBBM/CM 组减少 3.53±1.51mm（p=0.68）。在颊侧中央，AC 组牙槽嵴高度减少 0.10±1.30mm，而 DBBM/CM 组增加 0.77±2.43mm（p=0.10）。两组间垂直骨高度差异无统计学意义。AC 组和 DBBM/CM 组的体积吸收率分别为 12.37%±6.09%和 14.54%±11.21%，差异无统计学意义（p=0.36）。AC 组虚拟植入物周围平均骨密度（649.41±184.71HU）明显低于 DBBM/CM 组（985.23±207.85HU）（p<0.001）。
结论
与 DBBM/CM 相比，AC 用于 ARP 在限制牙槽嵴形态改变方面具有相似的效果。
Zotero 插件