Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, 117549Singapore.
Departments of Exercise and Nutrition Sciences and Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, DC, USA.
Br J Nutr. 2024 Apr 14;131(7):1236-1243. doi: 10.1017/S0007114523002647. Epub 2023 Nov 22.
Hand grip strength (HGS) is an important diagnostic tool for sarcopenia and a reliable predictor for age-related chronic diseases and mortality. Interventions in nutrition have been shown as a low-cost strategy to maintain muscular strength and mass. However, there are limited data on the effect of diet on HGS in Southeast Asian populations. This study aims to investigate the association of diet quality with HGS weakness and asymmetry in a multi-ethnic population in Singapore. This cross-sectional study used data from the Singapore Multi-Ethnic Cohort ( = 1547). Dietary data were collected using a validated semi-quantitative FFQ and summarised as the Dietary Quality Index - International (DQI-I). HGS was calculated as the maximum value of six measurements from both hands. HGS weakness and asymmetry were defined using well-recognised criteria. Multivariable linear regression and logistic regression were utilised for continuous and binary outcomes, respectively, adjusting for age, sex, ethnicity, physical activity and smoking status. It was found that the highest quartile of DQI-I was significantly associated with higher HGS ( = 1·11; 95 % CI 0·41, 1·82; < 0·001) and lower odds of HGS asymmetry (OR = 0·71; 95 % CI 0·53, 0·94; = 0·035) and both HGS weakness and asymmetry (OR = 0·50; 95 % CI 0·32, 0·76; = 0·004). Among the different components of DQI-I, only dietary adequacy was significantly associated with higher HGS ( < 0·001) and lower odds for both HGS weakness and asymmetry ( = 0·006). Our findings support that DQI-I, an indicator of overall diet quality, can be used to provide dietary guidelines for prevention and management of muscle wasting, sarcopenia and frailty.
握力是肌少症的重要诊断工具，也是与年龄相关的慢性疾病和死亡率的可靠预测指标。营养干预已被证明是维持肌肉力量和质量的低成本策略。然而，关于饮食对东南亚人群握力的影响的数据有限。本研究旨在调查饮食质量与新加坡多民族人群握力减弱和不对称的关系。这项横断面研究使用了新加坡多民族队列（n=1547）的数据。使用经过验证的半定量 FFQ 收集饮食数据，并将其总结为饮食质量指数-国际（DQI-I）。握力通过双手六次测量的最大值计算得出。握力减弱和不对称分别使用公认的标准定义。多变量线性回归和逻辑回归分别用于连续和二项结果，调整因素包括年龄、性别、种族、身体活动和吸烟状况。结果发现，DQI-I 的最高四分位数与较高的握力显著相关（β=1.11；95%CI 0.41，1.82；P<0.001），与握力不对称的几率降低相关（OR=0.71；95%CI 0.53，0.94；P=0.035），与握力减弱和不对称的几率降低均相关（OR=0.50；95%CI 0.32，0.76；P=0.004）。在 DQI-I 的不同组成部分中，只有饮食充足度与较高的握力显著相关（P<0.001），与握力减弱和不对称的几率降低均相关（P=0.006）。我们的研究结果支持 DQI-I 作为整体饮食质量的指标，可用于提供预防和管理肌肉减少症、肌少症和虚弱的饮食指南。
