School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, Australia.
PLoS Biol. 2023 Nov 22;21(11):e3002401. doi: 10.1371/journal.pbio.3002401. eCollection 2023 Nov.
There is a burgeoning appreciation for the wide-ranging effects of carbon dioxide on transcriptional regulation and metabolism. Here, Bolshette and colleagues provide the first link between carbon dioxide and the master transcriptional regulator of cholesterol homeostasis.
人们日益认识到二氧化碳对转录调控和代谢的广泛影响。在这里,Bolshette 及其同事首次发现了二氧化碳与胆固醇稳态主转录调控因子之间的联系。