Lindahl S
Acta Radiol Diagn (Stockh). 1986 Sep-Oct;27(5):513-8. doi: 10.1177/028418518602700505.
Retinoblastoma is the most common primary malignant intraocular tumor in children. The clinical features are leucocoria and/or strabismus. The ophthalmic diagnosis is straight forward in clear eye media with a white gray mass in the fundus. With opaque ocular media, other diagnostic procedures such as CT and ultrasonography are important. In the present study the results of CT examinations of 23 patients with histologically proven retinoblastomas are presented. The mean age of the patients was two years. The characteristic CT finding is a partly calcified intravitreous mass lesion mostly confined within the eyeball. Two cases showed retrobulbar extension and two intracranial tumor extension. No metastasis was found in the brain, liver, spleen, long bones, chest or skull. The radiologic screening procedures for retinoblastoma metastasis are discussed. In patients suspected to have a retinoblastoma, it is recommended to perform CT of the orbits and brain in order to detect the tumor and its possible retrobulbar and intracranial extension.
视网膜母细胞瘤是儿童最常见的原发性眼内恶性肿瘤。临床特征为白瞳症和/或斜视。在清澈的眼介质且眼底有灰白色肿块的情况下,眼科诊断较为直接。对于不透明的眼介质,CT和超声检查等其他诊断程序很重要。在本研究中,呈现了23例经组织学证实为视网膜母细胞瘤患者的CT检查结果。患者的平均年龄为2岁。CT的特征性表现是部分钙化的玻璃体内肿块病变,大多局限于眼球内。2例显示球后扩展,2例有颅内肿瘤扩展。在脑、肝、脾、长骨、胸部或颅骨中未发现转移。讨论了视网膜母细胞瘤转移的放射学筛查程序。对于疑似患有视网膜母细胞瘤的患者,建议进行眼眶和脑部CT检查,以检测肿瘤及其可能的球后和颅内扩展。