Barentsz J O, Rosenbusch G R, Strijk S P, Yap S H
Acta Radiol Diagn (Stockh). 1986 Sep-Oct;27(5):547-52. doi: 10.1177/028418518602700511.
The accuracy in the diagnosis of gastric cancer was investigated in 188 histologically proven cases, including 12 cases of early gastric cancer. One hundred and sixty-five of 167 patients (99%) were recorded radiologically as having a gastric lesion. The initial diagnosis was carcinoma in 144 patients (86%), and benign lesion in 21 cases (13%). In 2 cases (1%) no abnormalities were seen. In 3 out of 9 patients with a partial gastrectomy (33%) an incorrect diagnosis was made. In 11 of 12 patients with early gastric cancer the radiologic examination revealed abnormal findings, but 7 of these were incorrectly interpreted as benign. A retrospective analysis of the radiologic examination in which no malignancies were reported showed that inadequacy of the examination technique and misinterpretation of radiologic signs of malignancy were the main causes of failure in diagnosing of malignancy. The rate of misinterpretation of malignancy as a benign lesion (13%) justifies the endoscopic control of every radiologically detected abnormality. The high sensitivity in detecting a lesion indicates, however, that a biphasic radiologic examination is a safe screening method in gastric cancer. Endoscopy with biopsy showed a lesion in 156 out of 160 patients (98%), but in 11 of these (7%) the initial examination did not yield histologic proof of malignancy. In 4 patients (2%) no abnormalities were observed by endoscopists. One hundred and forty-nine patients were examined with both radiology and endoscopy with biopsy. A malignant lesion with recognition of its malignant character was defined in 144 cases (97%).
对188例经组织学证实的胃癌病例进行了诊断准确性的研究，其中包括12例早期胃癌。167例患者中有165例（99%）经放射学检查记录为有胃部病变。初始诊断为癌的患者有144例（86%），良性病变21例（13%）。2例（1%）未见异常。9例行部分胃切除术的患者中有3例（33%）诊断错误。12例早期胃癌患者中有11例经放射学检查发现异常，但其中7例被错误地解释为良性。对未报告恶性肿瘤的放射学检查进行回顾性分析表明，检查技术不足和对恶性肿瘤放射学征象的错误解读是诊断恶性肿瘤失败的主要原因。将恶性肿瘤误诊为良性病变的比例（13%）表明，对每例经放射学检查发现的异常情况都应进行内镜检查。然而，检测病变的高敏感性表明，双相放射学检查是一种安全的胃癌筛查方法。内镜活检显示，160例患者中有156例（98%）有病变，但其中11例（7%）的初始检查未获得恶性肿瘤的组织学证据。4例患者（2%）内镜检查未发现异常。149例患者同时接受了放射学检查和内镜活检。144例（97%）病例确定为具有恶性特征的恶性病变。
