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以主观支持为重点的认知行为疗法对(准)虚弱社区老年人抑郁症状的有效性:一项随机对照试验。

Effectiveness of subjective support-focused cognitive behavioral therapy on depressive symptoms among (pre)frail community-dwelling older adults: A randomized controlled trial.

作者信息

Wang Cuili, Si Huaxin, Bian Yanhui, Qiao Xiaoxia, Ji Lili, Liu Qinqin, Wang Wenyu, Yu Jiaqi, Li Yanyan, Zhou Wendie, Yue Weihua, Liu Jiajia, Jin Yaru

机构信息

Peking University, No. 38 Xueyuan Road, Beijing 100191, PR China.

Peking University Sixth Hospital, Peking University Institute of Mental Health, Beijing 100191, PR China.

出版信息

J Affect Disord. 2024 Feb 15;347:92-100. doi: 10.1016/j.jad.2023.11.058. Epub 2023 Nov 20.

DOI:10.1016/j.jad.2023.11.058
PMID:37992773
Abstract

BACKGROUND

Subjective support could ameliorate the adverse effect of (pre)frailty on depressive symptoms. However, there is scarce evidence regarding subjective support-focused intervention in preventing depression among (pre)frail community-dwelling older adults. This study aims to explore the effectiveness of subjective support-focused cognitive behavioral therapy (SS-CBT) in preventing depression among this group of population.

METHODS

A total of 100 community-dwelling (pre)frail older adults were recruited from six communities in a Chinese city and were randomized to an 8-week SS-CBT group or a wait-list control group. Depressive symptoms and subjective support were assessed at baseline (T0), and at 8 week (T1), 12 week (T2), 16 week (T3) after randomization. Generalized estimating equation was used to examine the effectiveness of SS-CBT on depressive symptoms and subjective support. Hierarchical linear regression models and Bootstrapping method were used to examine whether subjective support mediated the effectiveness of SS-CBT on depressive symptoms.

RESULTS

Participants in SS-CBT group reported significant reduction in depressive symptoms (Wald χ = 20.800, p < 0.001) and improvement in subjective support (Wald χ = 92.855, p < 0.001) compared to those in wait-list control group. Changes in subjective support mediated the effectiveness of SS-CBT on changes in depressive symptoms.

LIMITATIONS

Restricted regions to recruit participants, inclusion of the most motivated participants, lack of diagnosis of depression, potential experimenter bias and contamination, short follow-up period, and lack of an active control group.

CONCLUSIONS

The findings support the benefits of SS-CBT in preventing depression among (pre)frail community-dwelling older adults, and provide insight into possible mechanisms.

摘要

背景

主观支持可以减轻(轻度)虚弱对抑郁症状的不利影响。然而,关于以主观支持为重点的干预措施预防社区居住的(轻度)虚弱老年人抑郁的证据很少。本研究旨在探讨以主观支持为重点的认知行为疗法(SS-CBT)对这一人群预防抑郁的有效性。

方法

从中国一个城市的六个社区招募了100名社区居住的(轻度)虚弱老年人,并将他们随机分为8周的SS-CBT组或等待名单对照组。在基线(T0)以及随机分组后的第8周(T1)、第12周(T2)、第16周(T3)评估抑郁症状和主观支持。使用广义估计方程来检验SS-CBT对抑郁症状和主观支持的有效性。使用分层线性回归模型和自抽样法来检验主观支持是否介导了SS-CBT对抑郁症状的有效性。

结果

与等待名单对照组相比,SS-CBT组的参与者报告抑郁症状显著减轻(Wald χ = 20.800,p < 0.001),主观支持得到改善(Wald χ = 92.855,p < 0.001)。主观支持的变化介导了SS-CBT对抑郁症状变化的有效性。

局限性

招募参与者的地区有限,纳入了积极性最高的参与者,缺乏抑郁诊断, 存在潜在的实验者偏差和污染,随访期短,且缺乏积极对照组。

结论

研究结果支持SS-CBT对预防社区居住的(轻度)虚弱老年人抑郁的益处,并提供了对可能机制的见解。

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