Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Childhood Cancer Research Group, Danish Cancer Institute, Copenhagen, Denmark.
Br J Cancer. 2024 Feb;130(2):260-268. doi: 10.1038/s41416-023-02499-1. Epub 2023 Nov 22.
Survivors of childhood cancer may face difficulties at school. We investigated whether childhood cancer affects attainment of upper secondary education, in a register-based cohort study from Denmark, Finland, and Sweden, where we limit bias from selection and participation.
From the national cancer registers, we identified all long-term survivors of childhood cancer diagnosed aged 0-14 years in 1971-2005 (n = 7629), compared them to matched population comparisons (n = 35,411) and siblings (n = 6114), using odds ratios (OR) and 95% confidence intervals (CI).
Overall, 6127 survivors (80%) had attained upper secondary education by age 25, compared to 84% among comparison groups. Elevated OR for not attaining this level were mainly confined to survivors of central nervous system (CNS) tumours (OR2.05, 95%CI: 1.83-2.29). Other risk groups were survivors who had spent more time in hospital around cancer diagnosis and those who had hospital contacts in early adulthood, particularly psychiatric. Survivors of all cancer types were less likely to have attained upper secondary education without delay.
Although survivors of childhood cancer experienced delays in their education, many had caught up by age 25. Except for survivors of CNS tumours, survivors attained upper secondary education to almost the same extent as their peers.
儿童癌症幸存者在学校可能会面临困难。我们通过丹麦、芬兰和瑞典的一项基于登记的队列研究调查了儿童癌症是否会影响到中等继续教育的获得,该研究限制了选择和参与的偏差。
我们从国家癌症登记处确定了所有在 1971 年至 2005 年期间诊断为 0-14 岁的儿童癌症长期幸存者(n=7629),并将他们与匹配的人群对照组(n=35411)和兄弟姐妹(n=6114)进行比较,使用比值比(OR)和 95%置信区间(CI)。
总体而言,25 岁时有 6127 名幸存者(80%)达到了中等继续教育水平,而对照组的这一比例为 84%。未达到这一水平的幸存者的比值比升高主要局限于中枢神经系统(CNS)肿瘤的幸存者(OR2.05,95%CI:1.83-2.29)。其他风险群体是癌症诊断时住院时间较长的幸存者,以及在成年早期有住院接触的幸存者,尤其是精神病方面的幸存者。所有癌症类型的幸存者都不太可能不延迟获得中等继续教育。
尽管儿童癌症幸存者的教育受到了延迟,但许多人在 25 岁之前已经赶上了。除了中枢神经系统肿瘤的幸存者外,其他幸存者获得中等继续教育的程度几乎与同龄人相同。