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Whether early-stage (N0 neck) oral cancer patients received primary tumor resection without neck dissection benefit from immune checkpoint therapy.

作者信息

Liu Wei, Shen Xuemin, Shi Linjun, He Yue

机构信息

Department of Oral and Maxillofacial-Head and Neck Oncology, Fengcheng Hospital of Fengxian District, Shanghai Ninth People's Hospital Fengcheng Branch Hospital.

College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, People's Republic of China.

出版信息

Int J Surg. 2023 Nov 1;109(11):3715-3717. doi: 10.1097/JS9.0000000000000649.

DOI:10.1097/JS9.0000000000000649
PMID:37994732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10651285/
Abstract
摘要

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4
Elective neck dissection may not necessarily reduce recurrence and improve survival in all cases of early stage (CT1/2 N0 M0) oral squamous cell carcinoma.择期颈清扫术不一定能降低所有早期（CT1/2 N0 M0）口腔鳞状细胞癌患者的复发率和提高生存率。
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[The prognosis of neck dissection with sternocleidomastoid muscle preservation and resection in advanced oral squamous cell carcinoma: a retrospective cohort analysis].[保留与切除胸锁乳突肌的颈部清扫术治疗晚期口腔鳞状细胞癌的预后：一项回顾性队列分析]
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Evolutionary patterns and research frontiers in neoadjuvant immunotherapy: a bibliometric analysis.新辅助免疫治疗的演化模式与研究前沿：文献计量分析。
Int J Surg. 2023 Sep 1;109(9):2774-2783. doi: 10.1097/JS9.0000000000000492.
2
Lymph nodes: at the intersection of cancer treatment and progression.淋巴结：癌症治疗与进展的交汇点。
Trends Cell Biol. 2023 Dec;33(12):1021-1034. doi: 10.1016/j.tcb.2023.04.001. Epub 2023 May 4.
3
Toxicities associated with immune checkpoint inhibitors: a systematic study.免疫检查点抑制剂相关毒性：一项系统性研究。
Int J Surg. 2023 Jun 1;109(6):1753-1768. doi: 10.1097/JS9.0000000000000368.
4
A systematic review of neoadjuvant and definitive immunotherapy in locally advanced head and neck squamous cell carcinoma.局部晚期头颈部鳞状细胞癌新辅助和辅助免疫治疗的系统评价。
Cancer Med. 2023 May;12(10):11234-11247. doi: 10.1002/cam4.5815. Epub 2023 Mar 19.
5
Dynamic CD8 T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes.在转移性淋巴结中，癌症免疫治疗在人体区域淋巴结中诱导的动态 CD8 T 细胞反应被打乱。
Cell. 2023 Mar 16;186(6):1127-1143.e18. doi: 10.1016/j.cell.2023.02.021.
6
Immunotherapy and Biomarker Testing in Recurrent and Metastatic Head and Neck Cancers: ASCO Guideline.免疫治疗和生物标志物检测在复发性和转移性头颈部癌症中的应用：ASCO 指南。
J Clin Oncol. 2023 Feb 10;41(5):1132-1146. doi: 10.1200/JCO.22.02328. Epub 2022 Dec 15.
7
Elective Neck Dissection Versus Observation in cT1-T2 Oral Tongue Squamous Cell Carcinoma: A Meta-Analysis of 11,973 Patients.cT1-T2期口腔舌鳞状细胞癌的选择性颈部淋巴结清扫术与观察对比：11973例患者的荟萃分析
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):2256-2264. doi: 10.1007/s12070-020-02118-y. Epub 2020 Sep 2.
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J Maxillofac Oral Surg. 2022 Jun;21(2):340-349. doi: 10.1007/s12663-021-01677-z. Epub 2022 Jan 6.
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Elective neck dissection may not necessarily reduce recurrence and improve survival in all cases of early stage (CT1/2 N0 M0) oral squamous cell carcinoma.择期颈清扫术不一定能降低所有早期（CT1/2 N0 M0）口腔鳞状细胞癌患者的复发率和提高生存率。
J Evid Based Dent Pract. 2021 Jun;21(2):101573. doi: 10.1016/j.jebdp.2021.101573. Epub 2021 Apr 22.