胰腺癌中的组学科学与精准医学。

Omics sciences and precision medicine in pancreas cancer.

作者信息

Donato K, Micheletti C, Medori M C, Maltese P E, Tanzi B, Tezzele S, Mareso C, Generali D, Donofrio C A, Cominetti M, Fioravanti A, Riccio L, Beccari T, Ceccarini M R, Iaconelli A, Aquilanti B, Matera G, Ahmed R, Stuppia L, Gatta V, Cecchin S, Marceddu G, Bertelli M

机构信息

MAGI EUREGIO, Bolzano, Italy.

MAGISNAT, Peachtree Corners (GA), USA.

出版信息

Clin Ter. 2023 Nov-Dec;174(Suppl 2(6)):85-94. doi: 10.7417/CT.2023.2475.

DOI:10.7417/CT.2023.2475

PMID:37994752

Abstract

Pancreatic cancer is a leading cause of death worldwide, associated with poor prognosis outcomes and late treatment interventions. The pathological nature and extreme tissue heterogeneity of this disease has hampered all efforts to correctly diagnose and treat it. Omics sciences and precision medicine have revolutionized our understanding of pan-creatic cancer, providing a new hope for patients suffering from this devastating disease. By analyzing large-scale biological data sets and developing personalized treatment strategies, researchers and clinicians are working together to improve patient outcomes and ultimately find a cure for pancreatic cancer.

摘要

胰腺癌是全球主要的死亡原因之一，与预后不良和治疗干预延迟相关。这种疾病的病理性质和极端的组织异质性阻碍了所有正确诊断和治疗它的努力。组学科学和精准医学彻底改变了我们对胰腺癌的理解，为患有这种毁灭性疾病的患者带来了新的希望。通过分析大规模生物数据集并制定个性化治疗策略，研究人员和临床医生正在共同努力改善患者预后，并最终找到治愈胰腺癌的方法。