Clinical Microbiology and Parasitology Department, Basurto University Hospital, Avenida Montevideo 18, 48013, Bilbao, Vizcaya, Spain.
Biocruces Bizkaia Health Research Institute, Cruces Plaza, 48903, Barakaldo, Vizcaya, Spain.
Eur J Clin Microbiol Infect Dis. 2024 Feb;43(2):383-387. doi: 10.1007/s10096-023-04718-2. Epub 2023 Nov 24.
Two episodes of bacteremia of cutaneous origin in a female patient were caused by two unrelated Streptococcus canis isolates within 1-year interval between the two infection episodes. The most likelihood transmission route in both episodes was a dog pet that habitually licked patient´s legs. Isolates were characterised by antimicrobial susceptibility test and whole genome sequencing. They belonged to sequence type (ST) 40 and 43, respectively. The ST40 isolate harboured antimicrobial resistance genes aadE, ermB and tetO, displaying resistance to erythromycin, clindamycin and tetracyclines, while ST43 isolate did not presented any known antimicrobial resistance determinant and was susceptible to all antibiotics tested. S. canis infections are rare in human; however, attention is needed for patients at risk with companion animals.
一位女性患者在一年内发生了两起因皮肤来源的菌血症，这两起感染分别由两种不相关的犬链球菌分离株引起。在这两起感染中，最有可能的传播途径是一只经常舔舐患者腿部的宠物狗。分离株通过药敏试验和全基因组测序进行了特征描述。它们分别属于序列型 40 和 43。ST40 分离株携带 aadE、ermB 和 tetO 等抗菌药物耐药基因，对红霉素、克林霉素和四环素耐药，而 ST43 分离株未表现出任何已知的抗菌药物耐药决定因子，对所有测试的抗生素均敏感。人感染犬链球菌较为罕见；然而，需要对有宠物的高危患者加以关注。
