Leickly F E, Buckley R H
Am J Med. 1987 Jan;82(1):159-62. doi: 10.1016/0002-9343(87)90398-6.
A patient with common variable immunodeficiency and autoimmune hemolytic anemia was given high-dose (450 mg/kg) intravenous gamma globulin (Sandoglobulin) for five days, followed by single doses of 100 to 200 mg/kg at four-week intervals or whenever the hemoglobin level and hematocrit fell or the reticulocyte count increased. This treatment was accompanied by a stabilization of hematopoietic parameters and reversal of Coombs' positivity, which have been sustained for 34 months. The use of high-dose gamma globulin for autoimmune hemolytic anemia can eliminate the need for other therapeutic modalities that may be detrimental to an immunocompromised host.
一名患有常见变异型免疫缺陷和自身免疫性溶血性贫血的患者接受了为期五天的大剂量（450毫克/千克）静脉注射丙种球蛋白（沙格司亭）治疗，随后每隔四周或每当血红蛋白水平和血细胞比容下降或网织红细胞计数增加时给予100至200毫克/千克的单次剂量。这种治疗伴随着造血参数的稳定和库姆斯试验阳性的逆转，这种情况持续了34个月。使用大剂量丙种球蛋白治疗自身免疫性溶血性贫血可以消除对其他可能对免疫功能低下宿主有害的治疗方式的需求。
