Jo Sangyong, Park Kyungil
Division of Cardiology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.
Regional Cardiovascular Center, Dong-A University Hospital, Busan, Korea.
Korean J Gastroenterol. 2023 Nov 25;82(5):209-212. doi: 10.4166/kjg.2023.124.
Chronic liver disease causes hemodynamic changes in the body depending on the degree of progression. These hemodynamic changes begin with splanchnic vasodilation, with complications beginning to appear as the hyperdynamic changes occur. As chronic liver disease progresses, increased splanchnic vasodilation and hyperdynamic changes worsen portal hypertension and help cause or worsen chronic liver disease complications, such as ascites. Ultimately, the effective plasma volume and blood pressure decrease in the terminal stage.
慢性肝病会根据疾病进展程度导致身体出现血流动力学变化。这些血流动力学变化始于内脏血管舒张,随着高动力循环变化的出现,并发症开始显现。随着慢性肝病的进展,内脏血管舒张加剧和高动力循环变化会使门静脉高压恶化,并促使慢性肝病并发症(如腹水)的发生或恶化。最终,在终末期有效血容量和血压会下降。