Department of Stomatology, Shaoxing Yuecheng People's Hospital, 312000 Shaoxing, Zhejiang, China.
Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, 310000 Hangzhou, Zhejiang, China.
J Clin Pediatr Dent. 2023 Nov;47(6):142-149. doi: 10.22514/jocpd.2023.088. Epub 2023 Nov 3.
The aim was to investigate the relationship between time to hemostasis and pulpotomy outcomes with the use of iRoot BP Plus (Innovative Bioceramics, Vancouver, Canada) for young permanent teeth of patients aged from 7 to 12 with symptomatic irreversible pulpitis and evaluate the outcomes of pulpotomy. The present study was a prospective cohort study. Two hundred and six young permanent teeth with symptomatic irreversible pulpitis underwent pulpotomy with the use of iRoot BP Plus. All patients underwent pulpotomy in accordance with a standardized protocol. Patients were postoperatively re-called after 3, 6, 12 months. Successful cases were defined according to clinical and radiographic evaluations. Main outcome measures included tooth position, cave shape, previous restoration, preoperative symptoms, time to hemostasis and outcomes. On the basis of univariate linear regression model, the relationships between time to hemostasis was evaluated, and < 0.05 indicated a difference that achieved statistical significance. One hundred and ninety-three teeth can be evaluated after a follow-up for 6 to 36 months. The mean age of subjects was 9.43 ± 1.51 years. The overall clinical and radiographic success rate of pulpotomy reached 71.5% (138/193). After adjusting potential confounders (age, sex, previous restoration), non-linear relationship was detected between time to hemostasis and pulpotomy outcomes whose point was 4 minutes. The relationship between time to hemostasis and pulpotomy outcomes is non-linear. Pulpotomy outcomes was negatively related with time to hemostasis when time to hemostasis is more than 4 minutes.
目的是研究使用 iRoot BP Plus（加拿大温哥华创新生物陶瓷公司）对 7 至 12 岁有症状不可复性牙髓炎的年轻恒牙进行牙髓切断术的止血时间与牙髓切断术效果之间的关系，并评估牙髓切断术的效果。本研究为前瞻性队列研究。206 颗有症状不可复性牙髓炎的年轻恒牙采用 iRoot BP Plus 进行牙髓切断术。所有患者均按照标准化方案进行牙髓切断术。术后 3、6、12 个月对患者进行随访。根据临床和影像学评估成功病例。主要观察指标包括牙齿位置、窝洞形状、既往修复体、术前症状、止血时间和结果。基于单变量线性回归模型，评估止血时间与结果之间的关系，<0.05 表示差异具有统计学意义。在 6 至 36 个月的随访后，可评估 193 颗牙齿。受试者的平均年龄为 9.43±1.51 岁。牙髓切断术的总体临床和影像学成功率达到 71.5%（138/193）。在调整潜在混杂因素（年龄、性别、既往修复体）后，发现止血时间与牙髓切断术效果之间存在非线性关系，其拐点为 4 分钟。止血时间与牙髓切断术效果之间呈非线性关系。当止血时间超过 4 分钟时，止血时间与牙髓切断术效果呈负相关。
