Dentistry and Oral Surgery Department, Gulf Coast Veterinary Specialist, Houston, TX, USA.
Veterinary Dentistry Specialists, Katy, TX, USA.
J Vet Dent. 2024 Jul;41(4):312-323. doi: 10.1177/08987564231207208. Epub 2023 Nov 23.
This study aimed to assess if transient bacteremia developed from dental scaling, root planing (SRP) and dental extraction(s), if the bacteria originated from oral flora, and if the amount of bacteremia produced would warrant the use of pre-, intra-, or post-operative antibiotic therapy in healthy canine patients. Blood cultures were obtained from 13 healthy dogs with chronic periodontal disease that necessitated the extraction of one tooth or multiple teeth. Patients included did not receive any antibiotic therapy for a minimum of 2 weeks prior to their scheduled procedure and did not receive antibiotic therapy intra- or post-operatively. Blood collection occurred at specific time increments to determine the presence of bacteremia and if clearance of the bacteremia occurred post-procedure. The study found transient bacteremia developed at different time increments throughout the dental procedure. At the time of the final sample collection, no bacterial growth was evident in any of the blood cultures. Results of the blood cultures indicated that only four of 13 dogs had evidence of bacterial growth at any one of the time increments; however, by the final collection, there was no bacterial growth suggesting the transient bacteremia had cleared without the use of systemic antimicrobial therapy. The study findings indicate that systemic antibiotic usage is not warranted for severe periodontal disease where an episode of transient bacteremia is produced from SRP and dental extractions in an otherwise healthy patient.
本研究旨在评估在健康犬只接受牙齿洁治、根面平整(SRP)和拔牙时,是否会发生一过性菌血症;如果发生菌血症,其来源是否为口腔菌群;以及产生的菌血症数量是否需要在术前、术中或术后使用抗生素治疗。从患有慢性牙周病的 13 只需要拔除一颗或多颗牙齿的健康犬只中采集血培养样本。在预定手术前,患者至少 2 周内未接受任何抗生素治疗,且术中或术后未接受抗生素治疗。在特定时间间隔采集血液样本,以确定是否存在菌血症以及术后菌血症是否清除。研究发现,在整个牙科手术过程中,不同时间间隔会发生一过性菌血症。在最后一次样本采集时,没有任何血液培养物显示细菌生长。血培养结果表明,只有 4 只犬在任何一个时间间隔都有细菌生长的证据;然而,在最后一次采集时,没有细菌生长,表明一过性菌血症在没有使用全身抗菌治疗的情况下已经清除。研究结果表明,对于严重牙周病患者,在接受 SRP 和拔牙时会发生一过性菌血症,在这种情况下,不需要使用全身性抗生素。