阻塞性睡眠呼吸暂停患者快速眼动睡眠时长与喉咽反流的相关性
Correlation Between Rapid Eye Movement Sleep Duration and Laryngopharyngeal Reflux in Patients with Obstructive Sleep Apnea.
作者信息
Wang Zhe, Li Shuhua, Zuo Chengcheng, Qin Jie, Wu Dahai
机构信息
Postgraduate Training Base of Jinzhou Medical University in the General Hospital of Northern Theater Command, Jinzhou, China.
Department of Otolaryngology, General Hospital of Northern Theater Command, Shenyang, China.
出版信息
Ear Nose Throat J. 2023 Nov 24:1455613231214653. doi: 10.1177/01455613231214653.
The aim of this study was to investigate the correlation between rapid eye movement (REM) sleep duration and laryngopharyngeal reflux (LPR) in patients with obstructive sleep apnea (OSA). In all, 99 patients with OSA were enrolled in this study, and the correlation between REM sleep duration and the severity of LPR was analyzed after the polysomnography (PSG) and reflux symptom index (RSI) scores were completed. Subsequently, a multiple linear regression analysis was performed to further clarify the factors affecting LPR. Partial correlation analysis showed that the REM sleep duration was positively correlated with the RSI scores ( = 0.236, = .022) after controlling for apnea-hypopnea index (AHI), body mass index (BMI), lowest oxygen saturation (LSO), age, and sex. The multiple linear regression analysis indicated that only REM sleep duration was a factor influencing LPR ( = 2.330, = .022). Our study found a correlation between REM sleep duration and LPR in OSA patients. The shorter the REM sleep duration, the less severe the LPR symptoms.
本研究旨在探讨阻塞性睡眠呼吸暂停（OSA）患者快速眼动（REM）睡眠时间与喉咽反流（LPR）之间的相关性。本研究共纳入99例OSA患者，在完成多导睡眠图（PSG）和反流症状指数（RSI）评分后，分析REM睡眠时间与LPR严重程度之间的相关性。随后，进行多元线性回归分析以进一步阐明影响LPR的因素。偏相关分析显示，在控制了呼吸暂停低通气指数（AHI）、体重指数（BMI）、最低血氧饱和度（LSO）、年龄和性别后，REM睡眠时间与RSI评分呈正相关（r = 0.236，P = 0.022）。多元线性回归分析表明，只有REM睡眠时间是影响LPR的一个因素（β = 2.330，P = 0.022）。我们的研究发现OSA患者的REM睡眠时间与LPR之间存在相关性。REM睡眠时间越短，LPR症状越轻。
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