Pellegrino Rebecca, Villani Stefania, Spagnolo Daniela, Carofalo Irene, Carrino Nico, Calcagnile Matteo, Alifano Pietro, Madaghiele Marta, Demitri Christian, Nitti Paola
Department of Engineering for Innovation, Campus Ecotekne, University of Salento, Via per Monteroni, 73100 Lecce, Italy.
Microbiotech s.r.l., Via A. Tamborino s.n.c., 73024 Maglie, Italy.
Biology (Basel). 2023 Nov 6;12(11):1404. doi: 10.3390/biology12111404.
In recent years, the enormous demand for swabs for clinical use has promoted their relevance and, consequently, brought the environmental issues due to their single use and lack of biodegradability to the attention of the healthcare industry. Swabs consist of a stick that facilitates their easy handling and manoeuvrability even in complex districts and an absorbent tip designed to uptake and release biological samples. In this study, we focused on the fabrication of an innovative biodegradable poly(vinyl alcohol) (PVA) nanofiber swab tip using the electrospinning technique. The innovative swab tip obtained showed comparable uptake and release capacity of protein and bacterial species ( and ) with those of the commercial foam-type swab. In this way, the obtained swab can be attractive and suitable to fit into this panorama due to its low-cost process, easy scalability, and good uptake and release capabilities.
近年来，临床用拭子的巨大需求提升了它们的重要性，因此，其一次性使用且缺乏生物降解性所带来的环境问题引起了医疗行业的关注。拭子由一根棒组成，这使得即使在复杂区域也便于操作和 maneuverability，还有一个用于吸收和释放生物样本的吸收性尖端。在本研究中，我们专注于使用静电纺丝技术制造一种创新的可生物降解聚乙烯醇（PVA）纳米纤维拭子尖端。所获得的创新拭子尖端在蛋白质和细菌种类（以及）的吸收和释放能力方面与商用泡沫型拭子相当。通过这种方式，所获得的拭子因其低成本工艺、易于扩大规模以及良好的吸收和释放能力而具有吸引力且适合融入这一局面。
